UniProt Accession

 CCNY_MOUSE; Q8BGU5; Q8CI87; Q9CYN5 

Genbank Protein ID

 AK017493; AK028696; AK076556; BC023321; BC035524 

Genbank Nucleotide ID

 BAB30772.1; BAC26071.1; BAC36391.1; AAH23321.1; AAH35524.1 

Protein Name

 Cyclin-Y 

Protein Synonyms/Alias

 Cyclin fold protein 1 

Gene Name

 Ccny 

Gene Synonyms/Alias

 Cfp1 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
72	ASTIFLSKSQTDVRE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Positive regulatory subunit of the cyclin-dependent kinase CDK14/PFTK1. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway (By similarity). Recruits CDK16 to the plasma membrane (By similarity). Positive regulatory subunit of the cyclin-dependent kinase CDK16. 

Sequence Annotation

 DOMAIN 143 265 Cyclin N-terminal.
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 25 25 Phosphoserine.
 MOD_RES 83 83 Phosphoserine.
 MOD_RES 102 102 Phosphoserine.
 MOD_RES 324 324 Phosphoserine.
 MOD_RES 326 326 Phosphoserine.
 LIPID 2 2 N-myristoyl glycine (By similarity).  

Keyword

 Alternative splicing; Cell cycle; Cell division; Cell membrane; Complete proteome; Cyclin; Lipoprotein; Membrane; Myristate; Phosphoprotein; Reference proteome; Ubl conjugation; Wnt signaling pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 341 AA 

Protein Sequence

Gene Ontology

 GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; ISS:UniProtKB.
 GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; ISS:UniProtKB.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.
 GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.
 GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.
 GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. 

Interpro

 IPR013763; Cyclin-like.
 IPR006671; Cyclin_N.
 IPR012399; Cyclin_Y. 

Pfam

 PF00134; Cyclin_N 

SMART

 SM00385; CYCLIN 

PROSITE

 PS00292; CYCLINS 

PRINTS