CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025796
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zipper, isoform C 
Protein Synonyms/Alias
  
Gene Name
 zip 
Gene Synonyms/Alias
 CG15792; Dmel_CG15792 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
13DRNDPELKYLSVERNacetylation[1]
79ILRDDIQKMNPPKFDacetylation[1]
656RTVSHLYKEQLAKLMacetylation[1]
1594EKRRGLVKQLRDLETacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; ATP-binding; Coiled coil; Complete proteome; Hydrolase; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1971 AA 
Protein Sequence
MSEEVDRNDP ELKYLSVERN QFNDPATQAE WTQKRLVWVP HENQGFVAAS IKREHGDEVE 60
VELAETGKRV MILRDDIQKM NPPKFDKVED MAELTCLNEA SVLHNIKDRY YSGLIYTYSG 120
LFCVVVNPYK KLPIYTEKIM ERYKGIKRHE VPPHVFAITD SAYRNMLGDR EDQSILCTGE 180
SGAGKTENTK KVIQFLAYVA ASKPKGSGAV PHPAVLIGEL EQQLLQANPI LEAFGNAKTV 240
KNDNSSRFGK FIRINFDASG FISGANIETY LLEKSRAIRQ AKDERTFHIF YQLLAGATPE 300
QREKFILDDV KSYAFLSNGS LPVPGVDDYA EFQATVKSMN IMGMTSEDFN SIFRIVSAVL 360
LFGSMKFRQE RNNDQATLPD NTVAQKIAHL LGLSVTDMTR AFLTPRIKVG RDFVTKAQTK 420
EQVEFAVEAI AKACYERMFK WLVNRINRSL DRTKRQGASF IGILDMAGFE IFELNSFEQL 480
CINYTNEKLQ QLFNHTMFIL EQEEYQREGI EWKFIDFGLD LQPTIDLIDK PGGIMALLDE 540
ECWFPKATDK TFVDKLVSAH SMHPKFMKTD FRGVADFAIV HYAGRVDYSA AKWLMKNMDP 600
LNENIVSLLQ GSQDPFVVNI WKDAEIVGMA QQALTDTQFG ARTRKGMFRT VSHLYKEQLA 660
KLMDTLRNTN PNFVRCIIPN HEKRAGKIDA PLVLDQLRCN GVLEGIRICR QGFPNRIPFQ 720
EFRQRYELLT PNVIPKGFMD GKKACEKMIQ ALELDSNLYR VGQSKIFFRA GVLAHLEEER 780
DFKISDLIVN FQAFCRGFLA RRNYQKRLQQ LNAIRIIQRN CAAYLKLRNW QWWRLYTKVK 840
PLLEVTKQEE KLVQKEDELK QVREKLDTLA KNTQEYERKY QQALVEKTTL AEQLQAEIEL 900
CAEAEESRSR LMARKQELED MMQELETRIE EEEERVLALG GEKKKLELNI QDLEEQLEEE 960
EAARQKLQLE KVQLDAKIKK YEEDLALTDD QNQKLLKEKK LLEERANDLS QTLAEEEEKA 1020
KHLAKLKAKH EATISELEER LHKDQQQRQE SDRSKRKIET EVADLKEQLN ERRVQVDEMQ 1080
AQLAKREEEL TQTLLRIDEE SATKATAQKA QRELESQLAE IQEDLEAEKA ARAKAEKVRR 1140
DLSEELEALK NELLDSLDTT AAQQELRSKR EQELATLKKS LEEETVNHEG VLADMRHKHS 1200
QELNSINDQL ENLRKAKTVL EKAKGTLEAE NADLATELRS VNSSRQENDR RRKQAESQIA 1260
ELQVKLAEIE RARSELQEKC TKLQQEAENI TNQLEEAELK ASAAVKSASN MESQLTEAQQ 1320
LLEEETRQKL GLSSKLRQIE SEKEALQEQL EEDDEAKRNY ERKLAEVTTQ MQEIKKKAEE 1380
DADLAKELEE GKKRLNKDIE ALERQVKELI AQNDRLDKSK KKIQSELEDA TIELEAQRTK 1440
VLELEKKQKN FDKILAEEKA ISEQIAQERD TAEREAREKE TKVLSVSREL DEAFDKIEDL 1500
ENKRKTLQNE LDDLANTQGT ADKNVHELEK AKRALESQLA ELKAQNEELE DDLQLTEDAK 1560
LRLEVNMQAL RSQFERDLLA KEEGAEEKRR GLVKQLRDLE TELDEERKQR TAAVASKKKL 1620
EGDLKEIETT MEMHNKVKED ALKHAKKLQA QVKDALRDAE EAKAAKEELQ ALSKEAERKV 1680
KALEAEVLQL TEDLASSERA RRAAETERDE LAEEIANNAN KGSLMIDEKR RLEARIATLE 1740
EELEEEQSNS EVLLDRSRKA QLQIEQLTTE LANEKSNSQK NENGRALLER QNKELKAKLA 1800
EIETAQRTKV KATIATLEAK IANLEEQLEN EGKERLLQQK ANRKMDKKIK ELTMNIEDER 1860
RHVDQHKEQM DKLNSRIKLL KRNLDETEEE LQKEKTQKRK YQRECEDMIE SQEAMNREIN 1920
SLKTKLRRTG GIGLSSSRLT GTPSSKRAGG GGGGDDSSVQ DESLDGEDSA N 1971 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:EC.
 GO:0003774; F:motor activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR027401; Myosin-like_IQ_dom.
 IPR001609; Myosin_head_motor_dom.
 IPR004009; Myosin_N.
 IPR002928; Myosin_tail.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00612; IQ
 PF00063; Myosin_head
 PF02736; Myosin_N
 PF01576; Myosin_tail_1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.