CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030505
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 GRIP and coiled-coil domain-containing protein 2 
Protein Synonyms/Alias
 cDNA FLJ33494 fis, clone BRAMY2003898, highly similar to Homo sapiens GRIP and coiled-coil domain containing 2 (GCC2), transcript variant 1, mRNA 
Gene Name
 GCC2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
32LPKEDLIKFAKKQMMubiquitination[1]
36DLIKFAKKQMMLIQKubiquitination[2]
72EGTGDIIKALTERLDubiquitination[1]
403EQGCVIEKLKSELAGacetylation[3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 448 AA 
Protein Sequence
MEDLVQDGVA SPATPGTGKS KLETLPKEDL IKFAKKQMML IQKAKSRCTE LEKEIEELRS 60
KPVTEGTGDI IKALTERLDA LLLEKAETEQ QCLSLKKENI KMKQEVEDSV TKMGDAHKEL 120
EQSHINYVKE IENLKNELMA VRSKYSEDKA NLQKQLEEAM NTQLELSEQL KFQNNSEDNV 180
KKLQEEIEKI RPGFEEQILY LQKQLDATTD EKKETVTQLQ NIIEANSQHY QKNINSLQEE 240
LLQLKAIHQE EVKELMCQIE ASAKEHEAEI NKLNELKENL VKQCEASEKN IQKKYECELE 300
NLRKATSNAN QDNQICSILL QENTFVEQVV NEKVKHLEDT LKELESQHSI LKDEVTYMNN 360
LKLKLEMDAQ HIKDEFFHER EDLEFKINEL LLAKEEQGCV IEKLKSELAG LNKQFCYTVE 420
QHNREVQSLK EQHQKEISEL NETFLSDS 448 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS