CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011830
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 G protein-coupled receptor GPR1 
Protein Synonyms/Alias
  
Gene Name
 GPR1 
Gene Synonyms/Alias
 YDL035C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
368EIPTLFRKTNTGSDEubiquitination[1]
392LLDYNSAKPLDMSKYubiquitination[1]
908ENSIEEDKNLRYSDAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Seems to associate with GPA2 and act as G protein- coupled receptor that senses glucose and controls filamentous growth. It acts upstream of adenylate cyclase and is required for glucose activation of cAMP synthesis in concert with a glucose phosphorylation-dependent mechanism. 
Sequence Annotation
 MOD_RES 373 373 Phosphoserine.
 MOD_RES 903 903 Phosphoserine.  
Keyword
 Cell membrane; Complete proteome; G-protein coupled receptor; Membrane; Phosphoprotein; Receptor; Reference proteome; Transducer; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 961 AA 
Protein Sequence
MITEGFPPNL NALKGSSLLE KRVDSLRQLN TTTVNQLLGL PGMTSTFTAP QLLQLRIIAI 60
TASAVSLIAG CLGMFFLSKM DKRRKVFRHD LIAFLIICDF LKAFILMIYP MIILINNSVY 120
ATPAFFNTLG WFTAFAIEGA DMAIMIFAIH FAILIFKPNW KWRNKRSGNM EGGLYKKRSY 180
IWPITALVPA ILASLAFINY NKLNDDSDTT IILDNNNYNF PDSPRQGGYK PWSAWCYLPP 240
KPYWYKIVLS WGPRYFIIIF IFAVYLSIYI FITSESKRIK AQIGDFNHNV LEEEKEKKKL 300
FGLGHWGKAK WYFRSYFKLP LLHLLRNLKN FFTISFIDPN EETDDSGSSN GTFNFGESSN 360
EIPTLFRKTN TGSDENVSAS GGVRLLDYNS AKPLDMSKYA MSEQPDLERN NPFDCENDIT 420
LNPSELVSKQ KEHKVTFSVE NEGLDTRKSS MLGHQTFSCQ NSLESPLAMY DNKNDNSDIT 480
SNIKEKGGII NNNSNNDDDD NNNNNDNDND NNNSNNNNNN NNNNNNNNNN NNNNNNNNNN 540
NNNNSNNIKN NVDNNNTNPA DNIPTLSNEA FTPSQQFSQE RVNNNADRCE NSSFTNVQQH 600
FQAQTYKQMK KRRAQIQKNL RAIFIYPLSY IGIWLFPIIA DALQYNHEIK HGPTMWVTYI 660
DTCVRPLSCL VDVIVYLFKE KPWNYSWAKT ESKYLIEKYI LKGELGEKEI LKFCHSNWGK 720
RGWYYRGKWK KRKCWKYSTN PLKRILWFVE RFFKQLFELK LHFSFYDNCD DFEYWENYYS 780
AKDSNDNKRT ESDETKTNSS DRSLPSNSLE LQAMLNNITA EEVEVPLFWR IIHHIPMLGG 840
IDLDELNRLL KIRYNNDHFS LPGLKFALNQ NKSHDKHQDV STNSMVKSSF FSSNIVTNDD 900
ENSIEEDKNL RYSDASASEN YLVKPTIPGT TPDPIIEAQN DNDSSDSSGI DLIAFLRNGP 960
L 961 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0004930; F:G-protein coupled receptor activity; IMP:SGD.
 GO:0005536; F:glucose binding; IMP:SGD.
 GO:0051594; P:detection of glucose; IMP:SGD.
 GO:0009731; P:detection of sucrose stimulus; IMP:SGD.
 GO:0010255; P:glucose mediated signaling pathway; IMP:SGD.
 GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.
 GO:0007124; P:pseudohyphal growth; IMP:SGD.
 GO:0001302; P:replicative cell aging; IMP:SGD.
 GO:0009745; P:sucrose mediated signaling; IMP:SGD. 
Interpro
 IPR022596; Glucose_rcpt_Git3_C.
 IPR023041; Glucose_rcpt_Git3_N. 
Pfam
 PF11710; Git3
 PF11970; Git3_C 
SMART
  
PROSITE
  
PRINTS