CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA FLJ76216, highly similar to Homo sapiens xeroderma pigmentosum, complementation group C (XPC), mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
50PKKSLLSKVSQGKRKubiquitination[1]
161SRSLLPVKPVEIEIEubiquitination[1]
183RERSEKIKLEFETYLubiquitination[1]
374KQEETFAKGTCRPSAubiquitination[1]
650NHPLYALKRHLLKYEubiquitination[1]
849KRALGNWKLLAKGLLubiquitination[1]
853GNWKLLAKGLLIRERubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 940 AA 
Protein Sequence
MARKRAAGGE PRGRELRSQK SKAKSKARRE EEEEDAFEDE KPPKKSLLSK VSQGKRKRGC 60
SHPGGSADGP AKKKVAKVTV KSENLKVIKD EALSDGDDLR DFPSDLKKAH HLKRGATMNE 120
DSNEEEEESE NDWEEVEELS EPVLGDVRES TAFSRSLLPV KPVEIEIETP EQAKTRERSE 180
KIKLEFETYL RRAMKRFNKG VHEDTHKVHL LCLLANGFYR NNICSQPDLH AIGLSIIPAR 240
FTRVLPRDVD TYYLSNLVKW FIGTFTVNAE LSASEQDNLQ TTLERRFAIY SARDDEELVH 300
IFLLILRALQ LLTRLVLSLQ PIPLKSATAK GKKPSKERLT ADPGGSSETS SQVLENHTKP 360
KTSKGTKQEE TFAKGTCRPS AKGKRNKGGR KKRSKPSSSE EDEGPGDKQE KATQRRPHGR 420
ERRVASRVSY KGESGSDEAG SGSDFELSSG EASDPSDEDS EPGPPKQRKA PAPQRTKAGS 480
KSASRTHRGS HRKDPSLPAA SSSSSSSKRG KKMCSDGEKA EKRSIAGIDQ WLEVFCEQEE 540
KWVCVDCVHG VVGQPLTCYK YATKPMTYVV GIDSDGWVRD VTQRYDPVWM TVTRKCRVDA 600
EWWAETLRPY QSPFMDREKK EDLEFQAKHM DQPLPTAIGL YKNHPLYALK RHLLKYEAIY 660
PETAAILGYC RGEAVYSRDC VHTLHSRDTW LKKARVVRLG EVPYKMVKGF SNRARKARLA 720
EPQLREENDL GLFGYWQTEE YQPPVAVDGK VPRNEFGNVY LFLPSMMPIG CVQLNLPNLH 780
RVARKLDIDC VQAITGFDFH GGYSHPVTDG YIVCEEFKDV LLTAWENEQA VIERKEKEKK 840
EKRALGNWKL LAKGLLIRER LKRRYGPKSE AAAPHTDAGG GLSSDEEEGT SSQAEAARIL 900
AASWPQNREG EEKQKLKGGP KKTKREKKAA ASHLFPFEQL 940 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0003684; F:damaged DNA binding; IEA:InterPro.
 GO:0006289; P:nucleotide-excision repair; IEA:InterPro. 
Interpro
 IPR004583; DNA_repair_Rad4.
 IPR018026; DNA_repair_Rad4_subgr.
 IPR018325; Rad4/PNGase_transGLS-fold.
 IPR018326; Rad4_beta-hairpin_dom1.
 IPR018327; Rad4_beta-hairpin_dom2.
 IPR018328; Rad4_beta-hairpin_dom3. 
Pfam
 PF10403; BHD_1
 PF10404; BHD_2
 PF10405; BHD_3
 PF03835; Rad4 
SMART
 SM01030; BHD_1
 SM01031; BHD_2
 SM01032; BHD_3 
PROSITE
  
PRINTS