| Tag | Content |
|---|
| CPLM ID | CPLM-018713 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Carnitine O-palmitoyltransferase 1, muscle isoform |
Protein Synonyms/Alias | CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B |
Gene Name | Cpt1b |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 209 | YRMETLAKEFQDKTA | ubiquitination | [1] | | 321 | NTTRIPGKETDLLQH | ubiquitination | [1] | | 380 | PPQPGEEKLAALTAG | ubiquitination | [1] | | 621 | AFVQAMMKGSHKKQD | ubiquitination | [1] | | 626 | MMKGSHKKQDLQDLF | ubiquitination | [1] | | 766 | LDIAELFKISKTDS* | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | REGION 555 567 Coenzyme A binding (By similarity).
ACT_SITE 473 473 Proton acceptor (By similarity).
BINDING 589 589 Carnitine (By similarity).
BINDING 602 602 Carnitine (By similarity). |
Keyword | Acyltransferase; Complete proteome; Fatty acid metabolism; Lipid metabolism; Membrane; Mitochondrion; Mitochondrion outer membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 772 AA |
Protein Sequence | MAEAHQAVAF QFTVTPDGVD FRLSREALRH IYLSGINSWK KRLIRIKNGI LRGVYPGSPT 60
SWLVVVMATV GSNYCKVDIS MGLVDCIQRC LPERYGHFGT PQTEALLSMV IFSTGVWATG 120
IFFFRQTLKL LLSYHGWMFE MHSKTSHATK IWAICVRLLS SRRPMLYSFQ TSLPKLPVPS 180
VPATIHRYLD SVRPLLDDEA YYRMETLAKE FQDKTAPRLQ KYLVLKSWWA TNYVSDWWEE 240
YVYLRSRSPL MVNSNYYAMD FVLIKNTNVQ AARLGNAVHA MIMYRRKLDR EEIKPVMALG 300
MVPMCSYQME RMFNTTRIPG KETDLLQHLS ESRHVAVYHK GRFFKVWLYE GSRLLKPRDL 360
EMQFQRILDD PSPPQPGEEK LAALTAGGRV EWAEARQTFF SSGKNKMSLD AIERAAFFVT 420
LDEDSHCYNP DDETSLSLYG KALLHGNCYN RWFDKSFTLI SCKNGLLGLN TEHSWADAPI 480
IGHLWEFVLG TDTFHLGYTE TGHCVGEPNT TLPPPQRLPW DIPEQCREAI ENSYQVAKAL 540
ADDVELYCFQ FLPFGKGLIK KCRTSPDAFV QIALQLAHFR DKGKFCLTYE ASMTRMFREG 600
RTETVRSCTN ESAAFVQAMM KGSHKKQDLQ DLFRKASEKH QNMYRLAMTG AGIDRHLFCL 660
YIVSKYLGVS SPFLAEVLSE PWSLSTSQIP QFQICMFDPK QYPNHLGAGG GFGPVADDGY 720
GVSYMIAGEN TMFFHISSKY SSSETNAQRF GNHIRQALLD IAELFKISKT DS 772 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005741; C:mitochondrial outer membrane; TAS:MGI. GO:0004095; F:carnitine O-palmitoyltransferase activity; TAS:MGI. GO:0006635; P:fatty acid beta-oxidation; IEA:UniProtKB-UniPathway. GO:0015909; P:long-chain fatty acid transport; TAS:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |