CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001431
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MAGUK p55 subfamily member 3 
Protein Synonyms/Alias
 Discs large homolog 3; Protein MPP3 
Gene Name
 Mpp3 
Gene Synonyms/Alias
 Dlg3; Dusp3 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
48KSLGYLMKIHEKLRYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
 DOMAIN 6 60 L27 1.
 DOMAIN 61 118 L27 2.
 DOMAIN 137 218 PDZ.
 DOMAIN 226 296 SH3.
 DOMAIN 385 570 Guanylate kinase-like.  
Keyword
 Complete proteome; Reference proteome; Repeat; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 585 AA 
Protein Sequence
MPVLSEDSGL HETLALLTSQ LRPDSNHREE MGFLRDVFSE KSLGYLMKIH EKLRYYERQS 60
PTPVLHSAMA LAEDVMEELQ AASVHSDERE LLQLLSTPHL RAVLMVHDTV AQKNFDPVLP 120
PLPDNIDEDF EEESVKIVRL VKNKEPLGAT IRRDEHSGAV VVARIMRGGA ADRSGLVHVG 180
DELREVNGIT VLHKRPDEIS QILAQSQGSI TLKIIPATQE EDRFKESKVF MRALFHYDPR 240
EDRAIPCQEA GLPFQQRQVL EVVSQDDPTW WQAKRVGDTN LRAGLIPSKQ FQERRLSYRR 300
TTGTIPSPQN LRKPLYDQPC DKETCDCDGY FKGHYVAGLR RSFRLGCRER LTGSQEVKVP 360
VGAESQVLLT YEEVARYQHQ PGERSRLVVL IGSLGAHLHE LKQRVVAEDP QHFGVAVPHT 420
TRPRKSHERE GVEYHFVSKQ AFEADIQHNK FLEHGEHKEN LYGTSLEAIQ TVMAKNKVCL 480
VDVEPEALRH LRTPEFKPYV IFVKPAIQEK RKTPPVSPDS EDPATPLDEQ QQEMAASAAF 540
IDQHYGHLID TVLVRQDLQS VCSQLRAVIE SLSKDTYWVP ISWVR 585 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara. 
Interpro
 IPR008144; Guanylate_kin.
 IPR008145; Guanylate_kin/L-typ_Ca_channel.
 IPR020590; Guanylate_kinase_CS.
 IPR004172; L27.
 IPR014775; L27_C.
 IPR027417; P-loop_NTPase.
 IPR001478; PDZ.
 IPR001452; SH3_domain. 
Pfam
 PF00625; Guanylate_kin
 PF02828; L27
 PF00595; PDZ 
SMART
 SM00072; GuKc
 SM00569; L27
 SM00228; PDZ
 SM00326; SH3 
PROSITE
 PS00856; GUANYLATE_KINASE_1
 PS50052; GUANYLATE_KINASE_2
 PS51022; L27
 PS50106; PDZ
 PS50002; SH3 
PRINTS