CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020597
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-rich repeat-containing protein 40 
Protein Synonyms/Alias
  
Gene Name
 Lrrc40 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
141NVSHNKLKILPEEITubiquitination[1]
151PEEITSLKNLRTLHLubiquitination[1]
409KLLDYSDKQATLIPDacetylation[2]
508NLSFNRFKVFPEVLYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
 REPEAT 35 58 LRR 1.
 REPEAT 81 103 LRR 2.
 REPEAT 104 126 LRR 3.
 REPEAT 127 149 LRR 4.
 REPEAT 150 172 LRR 5.
 REPEAT 174 195 LRR 6.
 REPEAT 196 219 LRR 7.
 REPEAT 221 241 LRR 8.
 REPEAT 242 266 LRR 9.
 REPEAT 268 287 LRR 10.
 REPEAT 288 310 LRR 11.
 REPEAT 311 334 LRR 12.
 REPEAT 336 356 LRR 13.
 REPEAT 398 421 LRR 14.
 REPEAT 424 447 LRR 15.
 REPEAT 449 470 LRR 16.
 REPEAT 471 494 LRR 17.
 REPEAT 496 517 LRR 18.
 REPEAT 519 540 LRR 19.
 REPEAT 541 564 LRR 20.
 REPEAT 566 587 LRR 21.
 MOD_RES 71 71 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Leucine-rich repeat; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 602 AA 
Protein Sequence
MSRHMRAPRF DPRAGFHAEG KDRGPSVPQG LLKAARSSGQ LNLAGRNLGE VPQCVWRINV 60
DIPEEANQNL SFSSTERWWD QTDLTKLIIS SNKLQSLSDD LRLLPALTVL DIHDNQLTSL 120
PSAIRELDNL QKLNVSHNKL KILPEEITSL KNLRTLHLQH NELTCIPEGF EHLSCLEDLD 180
LSSNRLATVP ADFALLSSLL RLNLSSNQLK NLPAEISRMK RLKHLDCDAN LLETVPPDVG 240
SMESLELLYL RRNKLRVLPE FPSCRQLKEL HLAENQIEKL GAEHLQHLQA ILVLDLRGNK 300
LRSVPEEMAL LQSLERLDLS NNDISSLPCS LGNLHLKFLA LEGNPLRTIR REIIAKGTQE 360
VLKYLRSKIK DDRTNQNDSV PETAMTLPSE ARVNIHAIAT LKLLDYSDKQ ATLIPDDLFD 420
ATKTTLITSI NFSKNQLCEI PQRIVELKEM VLDINLSFNK LSFISHELCL LQKLTFLDLR 480
NNFLSSLPEE MSSLTKLQTI NLSFNRFKVF PEVLYRISTL EAVLISNNQV GSVDPQKMKL 540
MENLNTLDLQ NNDLLQIPPE LGNCVQLRTL LLDGNPFRVP RAAILMKGTA AVLEYLRDRI 600
PA 602 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003591; Leu-rich_rpt_typical-subtyp.
 IPR015766; Leu_rich_rpt-containing_40. 
Pfam
 PF00560; LRR_1
 PF12799; LRR_4 
SMART
 SM00369; LRR_TYP 
PROSITE
 PS51450; LRR 
PRINTS