UniProt Accession

 LY6K_HUMAN; Q17RY6; G3V116; O15227; Q9BVD7 

Genbank Protein ID

 AJ001348; AC108002; CH471162; BC001291; BC117142; BC117144; AI740834 

Genbank Nucleotide ID

 CAA04692.1; EAW82311.1; AAH01291.2; AAI17143.1; AAI17145.1 

Protein Name

 Lymphocyte antigen 6K 

Protein Synonyms/Alias

 Ly-6K 

Gene Name

 LY6K 

Gene Synonyms/Alias

 CO16 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
61	CQNPRRCKWTEPYCV	ubiquitination	[1, 2]
73	YCVIAAVKIFPRFFM	ubiquitination	[1, 2]
83	PRFFMVAKQCSAGCA	ubiquitination	[1]
96	CAAMERPKPEEKRFL	ubiquitination	[1]
100	ERPKPEEKRFLLEEP	ubiquitination	[1, 2]
114	PMPFFYLKCCKIRYC	ubiquitination	[1, 2]
117	FFYLKCCKIRYCNLE	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572] 

Functional Description

 May play a role in cell growth. 

Sequence Annotation

 DOMAIN 47 141 UPAR/Ly6.
 LIPID 138 138 GPI-anchor amidated glycine (Potential).
 CARBOHYD 20 20 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Cell membrane; Complete proteome; Cytoplasm; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0005730; C:nucleolus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS