CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002891
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable ubiquinone biosynthesis protein UbiB 
Protein Synonyms/Alias
  
Gene Name
 ubiB 
Gene Synonyms/Alias
 aarF; yigQ; yigR; yigS; b3835; JW3812 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
168PVIKADLKLIYRLARacetylation[1]
198EVVREYEKTLIDELNacetylation[1]
484YLQHSVDKIARELQSacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis. Specific for aerobically grown log-phase cells. 
Sequence Annotation
  
Keyword
 Cell inner membrane; Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Ubiquinone biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 546 AA 
Protein Sequence
MTPGEVRRLY FIIRTFLSYG LDELIPKMRI TLPLRLWRYS LFWMPNRHKD KLLGERLRLA 60
LQELGPVWIK FGQMLSTRRD LFPPHIADQL ALLQDKVAPF DGKLAKQQIE AAMGGLPVEA 120
WFDDFEIKPL ASASIAQVHT ARLKSNGKEV VIKVIRPDIL PVIKADLKLI YRLARWVPRL 180
LPDGRRLRPT EVVREYEKTL IDELNLLRES ANAIQLRRNF EDSPMLYIPE VYPDYCSEGM 240
MVMERIYGIP VSDVAALEKN GTNMKLLAER GVQVFFTQVF RDSFFHADMH PGNIFVSYEH 300
PENPKYIGID CGIVGSLNKE DKRYLAENFI AFFNRDYRKV AELHVDSGWV PPDTNVEEFE 360
FAIRTVCEPI FEKPLAEISF GHVLLNLFNT ARRFNMEVQP QLVLLQKTLL YVEGVGRQLY 420
PQLDLWKTAK PFLESWIKDQ VGIPALVRAF KEKAPFWVEK MPELPELVYD SLRQGKYLQH 480
SVDKIARELQ SNHVRQGQSR YFLGIGATLV LSGTFLLVSR PEWGLMPGWL MAGGLIAWFV 540
GWRKTR 546 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0019168; F:2-octaprenylphenol hydroxylase activity; IMP:EcoCyc.
 GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
 GO:0006744; P:ubiquinone biosynthetic process; IMP:EcoCyc. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR010232; UbiB.
 IPR004147; UbiB_dom. 
Pfam
 PF03109; ABC1 
SMART
  
PROSITE
  
PRINTS