CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000297
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin-like protein KIF3C 
Protein Synonyms/Alias
  
Gene Name
 KIF3C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
488LVSEEKQKLLEEKEKubiquitination[1]
493KQKLLEEKEKMLEDLubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
 Microtubule-based anterograde translocator for membranous organelles (By similarity). 
Sequence Annotation
 DOMAIN 1 375 Kinesin-motor.
 NP_BIND 97 104 ATP.
 REGION 630 793 Globular (Potential).  
Keyword
 3D-structure; ATP-binding; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Motor protein; Nucleotide-binding; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 793 AA 
Protein Sequence
MASKTKASEA LKVVARCRPL SRKEEAAGHE QILTMDVKLG QVTLRNPRAA PGELPKTFTF 60
DAVYDASSKQ ADLYDETVRP LIDSVLQGFN GTVFAYGQTG TGKTYTMQGT WVEPELRGVI 120
PNAFEHIFTH ISRSQNQQYL VRASYLEIYQ EEIRDLLSKE PGKRLELKEN PETGVYIKDL 180
SSFVTKNVKE IEHVMNLGNQ TRAVGSTHMN EVSSRSHAIF IITVECSERG SDGQDHIRVG 240
KLNLVDLAGS ERQNKAGPNT AGGAATPSSG GGGGGGGSGG GAGGERPKEA SKINLSLSAL 300
GNVIAALAGN RSTHIPYRDS KLTRLLQDSL GGNAKTIMVA TLGPASHSYD ESLSTLRFAN 360
RAKNIKNKPQ VNEDPKDTLL REFQEEIARL KAQLEKRGML GKRPRRKSSR RKKAVSAPPG 420
YPEGPVIEAW VAEEEDDNNN NHRPPQPILE SALEKNMENY LQEQKERLEE EKAAIQDDRS 480
LVSEEKQKLL EEKEKMLEDL RREQQATELL AAKYKAMESK LLIGGRNIMD HTNEQQKMLE 540
LKRQEIAEQK RREREMQQEM MLRDEETMEL RGTYTSLQQE VEVKTKKLKK LYAKLQAVKA 600
EIQDQHDEYI RVRQDLEEAQ NEQTRELKLK YLIIENFIPP EEKNKIMNRL FLDCEEEQWK 660
FQPLVPAGVS SSQMKKRPTS AVGYKRPISQ YARVAMAMGS HPRYRAENIM FLELDVSPPA 720
VFEMEFSHDQ EQDPRALHME RLMRLDSFLE RPSTSKVRKS RSWCQSPQRP PPSTTHASLA 780
SASLRPATVA DHE 793 
Gene Ontology
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005871; C:kinesin complex; TAS:ProtInc.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0003774; F:motor activity; TAS:ProtInc.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome.
 GO:0007596; P:blood coagulation; TAS:Reactome.
 GO:0007018; P:microtubule-based movement; TAS:Reactome. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.