CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019265
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein LTV1 homolog 
Protein Synonyms/Alias
  
Gene Name
 LTV1 
Gene Synonyms/Alias
 C6orf93 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
45RVLLPTQKIDNEERRubiquitination[1, 2]
127EDVGLLNKAAPVSGPubiquitination[1, 2, 3, 4]
237LFWSEETKSRFTEYSubiquitination[1]
303EVLNDYYKEKAENCVubiquitination[1, 3]
305LNDYYKEKAENCVKLubiquitination[1]
368YNHPQLIKYQPKPKQubiquitination[1]
374IKYQPKPKQIRISSKubiquitination[1]
381KQIRISSKTGIPLNVubiquitination[1, 2]
467EKELLNLKKNVEGLKubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
 MOD_RES 182 182 Phosphoserine.
 MOD_RES 188 188 Phosphoserine.
 MOD_RES 331 331 Phosphoserine.  
Keyword
 Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MPHRKKKPFI EKKKAVSFHL VHRSQRDPLA ADESAPQRVL LPTQKIDNEE RRAEQRKYGV 60
FFDDDYDYLQ HLKEPSGPSE LIPSSTFSAH NRREEKEETL VIPSTGIKLP SSVFASEFEE 120
DVGLLNKAAP VSGPRLDFDP DIVAALDDDF DFDDPDNLLE DDFILQANKA TGEEEGMDIQ 180
KSENEDDSEW EDVDDEKGDS NDDYDSAGLL SDEDCMSVPG KTHRAIADHL FWSEETKSRF 240
TEYSMTSSVM RRNEQLTLHD ERFEKFYEQY DDDEIGALDN AELEGSIQVD SNRLQEVLND 300
YYKEKAENCV KLNTLEPLED QDLPMNELDE SEEEEMITVV LEEAKEKWDC ESICSTYSNL 360
YNHPQLIKYQ PKPKQIRISS KTGIPLNVLP KKGLTAKQTE RIQMINGSDL PKVSTQPRSK 420
NESKEDKRAR KQAIKEERKE RRVEKKANKL AFKLEKRRQE KELLNLKKNV EGLKL 475 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR007307; LTV. 
Pfam
 PF04180; LTV 
SMART
  
PROSITE
  
PRINTS