| Tag | Content |
|---|
| CPLM ID | CPLM-009408 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Arginine biosynthesis bifunctional protein ArgJ |
Protein Synonyms/Alias | Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGSase; Arginine biosynthesis bifunctional protein ArgJ alpha chain; Arginine biosynthesis bifunctional protein ArgJ beta chain |
Gene Name | argJ |
Gene Synonyms/Alias | RPA0592 |
Created Date | July 27, 2013 |
Organism | Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) |
NCBI Taxa ID | 258594 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 34 | AAAGIRYKGRTDVLL | acetylation | [1] | | 289 | RDGEGARKLVEIIVE | acetylation | [1] |
|
Reference | [1] System-wide studies of N-lysine acetylation in Rhodopseudomonas palustris reveal substrate specificity of protein acetyltransferases. Crosby HA, Pelletier DA, Hurst GB, Escalante-Semerena JC. J Biol Chem. 2012 May 4;287(19):15590-601. [ PMID: 22416131] |
Functional Description | Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity). |
Sequence Annotation | ACT_SITE 195 195 Nucleophile (By similarity).
BINDING 158 158 Substrate (By similarity).
BINDING 184 184 Substrate (By similarity).
BINDING 195 195 Substrate (By similarity).
BINDING 285 285 Substrate (By similarity).
BINDING 408 408 Substrate (By similarity).
BINDING 413 413 Substrate (By similarity). |
Keyword | Acyltransferase; Amino-acid biosynthesis; Arginine biosynthesis; Autocatalytic cleavage; Complete proteome; Cytoplasm; Multifunctional enzyme; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 413 AA |
Protein Sequence | MSSKVSPLAP TDVPAMPMIA GVRLATAAAG IRYKGRTDVL LVEMEKGTTV AGVFTTSKCA 60
SAPVEWCRDK LKGGSARALV VNSGNANAFT GKSGKQAATL TAQLAAKAIG CKPAEVFLAS 120
TGVIGEPLDA TKFDGVLDAL ALDAGPDGWM DAAKAIMTTD TFPKVATATV KLGKAKVTIN 180
GMAKGAGMIA PDMATMLSFI FTDAPLSASC LQALLKAGVT DTFNAVTIDG DTSTSDTLLA 240
FATGAAAENG APKISRASDP RLKAFVKAFN AVLADLAEQV ARDGEGARKL VEIIVEGAKT 300
KVSARKIALS IANSPLVKTA IAGEDANWGR VVMAVGKAGE PADRDKLSIS FNGIRVAKAG 360
ARDPSYNEKE VSAEMKKPVI QIKVALGLGK GRDRVLTCDL TKEYVAINGD YRS 413 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004042; F:acetyl-CoA:L-glutamate N-acetyltransferase activity; IEA:HAMAP. GO:0004358; F:glutamate N-acetyltransferase activity; IEA:HAMAP. GO:0006526; P:arginine biosynthetic process; IEA:HAMAP. |
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Pfam | |
SMART | |
PROSITE | |
PRINTS | |