CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033169
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Caldesmon 
Protein Synonyms/Alias
  
Gene Name
 CALD1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
174TVTKSYQKNDWRDAEacetylation[1]
400ERAEFLNKSVQKSSGacetylation[2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 459 AA 
Protein Sequence
MDDFERRREL RRQKREEMRL EAERIAYQRN DDDEEEAARE RRRRARQERL RQKQEEESLG 60
QVTDQVEVNA QNSVPDEEAK TTTTNTQVEG DDEAAFLERL ARREERRQKR LQEALERQKE 120
FDPTITDASL SLPSRRMQND TAENETTEKE EKSESRQERY EIEETETVTK SYQKNDWRDA 180
EENKKEDKEK EEEEEEKPKR GSIGENQIKD EKIKKDKEPK EEVKSFMDRK KGFTEVKSQN 240
GEFMTHKLKH TENTFSRPGG RASVDTKEAE GAPQVEAGKR LEELRRRRGE TESEEFEKLK 300
QKQQEAALEL EELKKKREER RKVLEEEEQR RKQEEADRKL REEEEKRRLK EEIERRRAEA 360
AEKRQKMPED GLSDDKKPFK CFTPKGSSLK IEERAEFLNK SVQKSSGVKS THQAAIVSKI 420
DSRLEQYTSA IEGTKSAKPT KPAASDLPVP AEGVRNIKS 459 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0006936; P:muscle contraction; IEA:InterPro. 
Interpro
 IPR006017; Caldesmon.
 IPR006018; Caldesmon_LSP. 
Pfam
 PF02029; Caldesmon 
SMART
  
PROSITE
  
PRINTS
 PR01076; CALDESMON.