CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006837
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leu/Val/Ile amino-acid permease 
Protein Synonyms/Alias
 Branched-chain amino-acid permease 2 
Gene Name
 BAP2 
Gene Synonyms/Alias
 YBR068C; YBR0629 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
12EDFGSSGKKETSPDSubiquitination[1]
13DFGSSGKKETSPDSIubiquitination[1]
38FQSSSSEKTYSKQKSubiquitination[1]
59HRFADSFKRAEGSTTubiquitination[1]
69EGSTTRTKQINENTSubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Permease for leucine, valine and isoleucine. Also transports cysteine, methionine, phenyalanine, tyrosine and tryptophan. 
Sequence Annotation
 MOD_RES 3 3 Phosphoserine.
 MOD_RES 15 15 Phosphothreonine.
 MOD_RES 16 16 Phosphoserine.
 MOD_RES 19 19 Phosphoserine.
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 24 24 Phosphoserine.
 MOD_RES 76 76 Phosphoserine.
 MOD_RES 84 84 Phosphoserine.  
Keyword
 Amino-acid transport; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 609 AA 
Protein Sequence
MLSSEDFGSS GKKETSPDSI SIRSFSAGNN FQSSSSEKTY SKQKSGSDKL IHRFADSFKR 60
AEGSTTRTKQ INENTSDLED GVESITSDSK LKKSMKSRHV VMMSLGTGIG TGLLVANAKG 120
LHYGGPAALI IGYILVSFVT YFMIQAAGEM AVTYPTLPAN FNAYSSIFIS KSFGFATVWL 180
YCFQWLTVLP LELITASMTI QFWNDKINPD IYILIFYVFL VFIHFFGVKA YGETEFIFNC 240
CKILMIAGFI ILSIVINCGG AGNDGYIGAT YWHNPGAFAG DTSIGRFKNV CYILVTAYFS 300
FGGMELFALS VQEQSNPRKS TPVAAKRSIY RIVVIYLLTM ILIGFNVPYN DDQLMGAGGS 360
ATHASPYVLA ASIHGVKIVP HIINAVILIS VVSVANSSLY AGPRLICSLA QQGYAPKFLD 420
YVDREGRPLR ALIVCCVFGV IAFVAASSKE EIVFTWLAAI AGLSELFTWT SIMLSHLRFR 480
QAMKVQGRSL DELGYKATTG IWGSIYGVFF NILVFVAQFW VALAPLGNGG KCDAESFFQN 540
YLAFPIWLAF YFGYMVYNRD FTLLNPLDKI DLDFHRRIYD PELMRQEDEE NKEKLRNMSL 600
MRKAYHFWC 609 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; ISS:SGD.
 GO:0015171; F:amino acid transmembrane transporter activity; IDA:SGD. 
Interpro
 IPR004841; AA-permease_dom.
 IPR002293; AA/rel_permease1.
 IPR004762; Amino_acid_permease_fungi.
 IPR004840; Amoino_acid_permease_CS. 
Pfam
 PF00324; AA_permease 
SMART
  
PROSITE
 PS00218; AMINO_ACID_PERMEASE_1 
PRINTS