| Tag | Content |
|---|
| CPLM ID | CPLM-015399 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Choline dehydrogenase, mitochondrial |
Protein Synonyms/Alias | CDH; CHD |
Gene Name | Chdh |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 80 | LLLEAGPKDLLMGSK | acetylation | [1] | | 87 | KDLLMGSKRLQWKIH | acetylation | [1] | | 174 | HCLPYFRKAQKHELG | acetylation | [1] | | 177 | PYFRKAQKHELGANM | acetylation | [1] | | 284 | AVGVEYIKDGQSHKA | acetylation | [1] | | 290 | IKDGQSHKAYVSREV | acetylation | [1] | | 441 | ATSVGWLKLRSTNPQ | acetylation | [1] | | 489 | AFAPFRGKELQPGSH | acetylation | [1] | | 501 | GSHVQSDKEIDAFVR | acetylation | [1] | | 591 | DENVPVYKPQTLDTQ | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | |
Sequence Annotation | NP_BIND 47 79 FAD (By similarity).
ACT_SITE 516 516 By similarity.
MOD_RES 501 501 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Direct protein sequencing; FAD; Flavoprotein; Membrane; Mitochondrion; Mitochondrion inner membrane; Oxidoreductase; Reference proteome; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 599 AA |
Protein Sequence | MWQVLRSWSK RCLSPRGALA WAAQGQPRPP CSCAVASAAS GGKDEYTFIV VGAGSAGCVL 60
ANRLTEDPNH RVLLLEAGPK DLLMGSKRLQ WKIHMPAALV ANLCDDKYNW YYHTEAQPGL 120
DGRVLYWPRG RVWGGSSSLN AMVYIRGHAE DYNRWHRQGA EGWDYAHCLP YFRKAQKHEL 180
GANMYRGGDG PLHVSRGKTN HPLHQAFLQA ARQAGYPFTE DMNGFQQEGF GWMDMTIHQG 240
KRWSTASAYL RPALSRPNLR AEVQTLVSRV LFEGTRAVGV EYIKDGQSHK AYVSREVILS 300
GGAINSPQLL MLSGVGNADD LKKLGIPVVC HLPGVGQNLQ DHLEIYIQHA CTQPITLHSA 360
QKPLRKVCIG LEWLWRFTGD GATAHLETGG FIRSRPGVPH PDIQFHFLPS QVIDHGRKPT 420
QQEAYQVHVG TMRATSVGWL KLRSTNPQDH PMINPNYLST ETDVEDFRQC VKLTREIFAQ 480
EAFAPFRGKE LQPGSHVQSD KEIDAFVRAK ADSAYHPSCT CKMGQPSDPT AVVDQQTRVI 540
GVENLRVIDA SIMPSVVSGN LNAPTIMIAE KAADVIKGCP ALGDENVPVY KPQTLDTQR 599 |
Gene Ontology | GO:0005743; C:mitochondrial inner membrane; IDA:RGD. GO:0008812; F:choline dehydrogenase activity; IMP:RGD. GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. GO:0019285; P:glycine betaine biosynthetic process from choline; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |