UniProt Accession

 S39A7_HUMAN; Q92504; B0UXF6; Q5STP8; Q9UIQ0 

Genbank Protein ID

 D82060; AF117221; AL031228; AL645940; AL662824; AL844527; CR759786; CR936877; CR936877; CR759786; CR759733; CR354565; CH471081; BC000645 

Genbank Nucleotide ID

 BAA11528.1; AAD12305.1; CAA20238.1; CAI18067.1; CAI17615.1; CAI41839.1; CAQ08249.1; CAQ08249.1; CAQ09067.1; CAQ09067.1; CAQ10301.1; CAQ11085.1; EAX03680.1; AAH00645.1 

Protein Name

 Zinc transporter SLC39A7 

Protein Synonyms/Alias

 Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7 

Gene Name

 SLC39A7 

Gene Synonyms/Alias

 HKE4; RING5 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
310	PQNAEEEKRGLDLRV	ubiquitination	[1, 2, 3, 4]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

 MOD_RES 275 275 Phosphoserine.
 MOD_RES 276 276 Phosphoserine.
 CARBOHYD 330 330 N-linked (GlcNAc...) (Potential).
 CROSSLNK 310 310 Glycyl lysine isopeptide (Lys-Gly)  

Keyword

 Complete proteome; Glycoprotein; Ion transport; Isopeptide bond; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport; Ubl conjugation; Zinc; Zinc transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 469 AA 

Protein Sequence

Gene Ontology

 GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
 GO:0055085; P:transmembrane transport; TAS:Reactome.
 GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. 

Interpro

 IPR003689; ZIP. 

Pfam

 PF02535; Zip 

SMART

  

PROSITE

  

PRINTS