| Tag | Content |
|---|
| CPLM ID | CPLM-033672 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nuclear factor 1 |
Protein Synonyms/Alias | |
Gene Name | NFIX |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 63 | KDELLGEKPEIKQKW | ubiquitination | [1] |
|
Reference | [1] Integrated proteomic analysis of post-translational modifications by serial enrichment. Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA. Nat Methods. 2013 Jul;10(7):634-7. [ PMID: 23749302] |
Functional Description | Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication (By similarity). |
Sequence Annotation | |
Keyword | Activator; Complete proteome; DNA replication; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 460 AA |
Protein Sequence | MLPACRLQDE FHPFIEALLP HVRAFSYTWF NLQARKRKYF KKHEKRMSKD EERAVKDELL 60
GEKPEIKQKW ASRLLAKLRK DIRPEFREDF VLTITGKKPP CCVLSNPDQK GKIRRIDCLR 120
QADKVWRLDL VMVILFKGIP LESTDGERLY KSPQCSNPGL CVQPHHIGVT IKELDLYLAY 180
FVHTPESGQS DSSNQQGDAD IKPLPNGHLS FQDCFVTSGV WNVTELVRVS QTPVATASGP 240
NFSLADLESP SYYNINQVTL GRRSITSPPS TSTTKRPKSI DDSEMESPVD DVFYPGTGRS 300
PAAGSSQSSG WPNDVDAGSP RATASALHFP STSIIQQSSP YFTHPTIRYH HHHGQDSLKE 360
FVQFVCSDGS GQATGQPNGS GQGKVPGSFL LPPPPPVARP VPLPMPDSKS TSTAPDGAAL 420
TPPSPSFATT GASSANRFVS IGPRDGNFLN IPQQSQSWFL 460 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0006260; P:DNA replication; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |