UniProt Accession

 D3YXR4_MOUSE; D3YXR4 

Genbank Protein ID

 AC133502 

Genbank Nucleotide ID

  

Protein Name

 7-dehydrocholesterol reductase 

Protein Synonyms/Alias

  

Gene Name

 Dhcr7 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
18	KVKSPNGKAGSQGQW	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 225 AA 

Protein Sequence

Gene Ontology

 GO:0016020; C:membrane; IEA:InterPro.
 GO:0047598; F:7-dehydrocholesterol reductase activity; IDA:MGI.
 GO:0001568; P:blood vessel development; IMP:MGI.
 GO:0030154; P:cell differentiation; IMP:MGI.
 GO:0030324; P:lung development; IMP:MGI.
 GO:0035264; P:multicellular organism growth; IMP:MGI.
 GO:0009791; P:post-embryonic development; IMP:MGI.
 GO:0042127; P:regulation of cell proliferation; IMP:MGI.
 GO:0016126; P:sterol biosynthetic process; IMP:MGI. 

Interpro

 IPR001171; Ergosterol_biosynth_ERG4_ERG24.
 IPR018083; Sterol_reductase_CS. 

Pfam

 PF01222; ERG4_ERG24 

SMART

  

PROSITE

 PS01017; STEROL_REDUCT_1 

PRINTS