CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023939
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Sorting nexin-11 
Protein Synonyms/Alias
  
Gene Name
 SNX11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
98TSDEFIEKRRQGLQHubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
 Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes. 
Sequence Annotation
 DOMAIN 16 132 PX.
 REGION 135 139 Important for membrane trafficking.
 BINDING 59 59 Phosphatidylinositol 3-phosphate.
 BINDING 85 85 Phosphatidylinositol 3-phosphate (By
 BINDING 99 99 Phosphatidylinositol 3-phosphate (By  
Keyword
 3D-structure; Complete proteome; Endosome; Lipid-binding; Membrane; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 270 AA 
Protein Sequence
MGFWCRMSEN QEQEEVITVR VQDPRVQNEG SWNSYVDYKI FLHTNSKAFT AKTSCVRRRY 60
REFVWLRKQL QRNAGLVPVP ELPGKSTFFG TSDEFIEKRR QGLQHFLEKV LQSVVLLSDS 120
QLHLFLQSQL SVPEIEACVQ GRSTMTVSDA ILRYAMSNCG WAQEERQSSS HLAKGDQPKS 180
CCFLPRSGRR SSPSPPPSEE KDHLEVWAPV VDSEVPSLES PTLPPLSSPL CCDFGRPKEG 240
TSTLQSVRRA VGGDHAVPLD PGQLETVLEK 270 
Gene Ontology
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
 GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR001683; Phox. 
Pfam
 PF00787; PX 
SMART
 SM00312; PX 
PROSITE
 PS50195; PX 
PRINTS