| Tag | Content |
|---|
| CPLM ID | CPLM-011412 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Methylthioribose-1-phosphate isomerase |
Protein Synonyms/Alias | M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein |
Gene Name | MRI1 |
Gene Synonyms/Alias | YPR118W; P9642.7 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 124 | VEIKNILKSSSDLKA | ubiquitination | [1] | | 211 | DSLAKTDKADSGLDN | ubiquitination | [1] | | 220 | DSGLDNEKCPRMGHV | ubiquitination | [1] | | 273 | RTSPIPIKAAFVGAD | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P). |
Sequence Annotation | ACT_SITE 280 280 Proton donor (By similarity).
MOD_RES 351 351 Phosphoserine. |
Keyword | 3D-structure; Amino-acid biosynthesis; Complete proteome; Cytoplasm; Isomerase; Methionine biosynthesis; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 411 AA |
Protein Sequence | MSLEAIVFDR SEPENVSVKV LDQLLLPYTT KYVPIHTIDD GYSVIKSMQV RGAPAIAIVG 60
SLSVLTEVQL IKHNPTSDVA TLYSLVNWES TKTVLNKRLD FLLSSRPTAV NLSNSLVEIK 120
NILKSSSDLK AFDGSLYNYV CELIDEDLAN NMKMGDNGAK YLIDVLQKDG FKDEFAVLTI 180
CNTGSLATSG YGTALGVIRS LWKDSLAKTD KADSGLDNEK CPRMGHVFPL ETRPYNQGSR 240
LTAYELVYDK IPSTLITDSS IAYRIRTSPI PIKAAFVGAD RIVRNGDTAN KIGTLQLAVI 300
CKQFGIKFFV VAPKTTIDNV TETGDDIIVE ERNPEEFKVV TGTVINPENG SLILNESGEP 360
ITGKVGIAPL EINVWNPAFD ITPHELIDGI ITEEGVFTKN SSGEFQLESL F 411 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IDA:SGD. GO:0019284; P:L-methionine biosynthetic process from S-adenosylmethionine; IEA:HAMAP. GO:0019509; P:L-methionine salvage from methylthioadenosine; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |