Tag | Content |
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CPLM ID | CPLM-007581 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Signal peptidase complex catalytic subunit SEC11A |
Protein Synonyms/Alias | Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SPase 18 kDa subunit; SEC11 homolog A; SEC11-like protein 1; SPC18 |
Gene Name | Sec11a |
Gene Synonyms/Alias | Sec11l1; Spc18 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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110 | EKQDGHIKFLTKGDN | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). |
Sequence Annotation | ACT_SITE 56 56 By similarity. |
Keyword | Complete proteome; Endoplasmic reticulum; Hydrolase; Membrane; Microsome; Protease; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 179 AA |
Protein Sequence | MLSLDFLDDV RRMNKRQLYY QVLNFGMIVS SALMIWKGLM LITGSESPIV VVLSGSMEPA 60 FHRGDLLFLT NRVEDPIRVG EIVVFRIEGR EIPIVHRVLK IHEKQDGHIK FLTKGDNNAV 120 DDRGLYKQGQ HWLEKKDVVG RARGFVPYIG IVTILMNDYP KFSYAVLFLL GLFVLVHRE 179 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0008236; F:serine-type peptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. GO:0006465; P:signal peptide processing; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |