UniProt Accession

 B0BNL2_RAT; B0BNL2 

Genbank Protein ID

 AABR06053661; BC158867; CH473993 

Genbank Nucleotide ID

 AAI58868.1; EDL78356.1 

Protein Name

 PDZ domain-containing protein 2 

Protein Synonyms/Alias

 Peptidylprolyl cis/trans isomerase, NIMA-interacting 1; Protein (Peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 (Predicted), isoform CRA_a 

Gene Name

 LOC364561 

Gene Synonyms/Alias

 Pin1; Pin1_predicted; rCG_31594 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
48	STVGGGSKNGQGEPA	acetylation	[1]
84	QEKITRSKEEALELI	acetylation	[1]
134	FSRGQMQKPFEDASF	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Isomerase; Reference proteome; Rotamase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 165 AA 

Protein Sequence

Gene Ontology

 GO:0030496; C:midbody; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
 GO:2000146; P:negative regulation of cell motility; IEA:Compara.
 GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Compara.
 GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IEA:Compara.
 GO:0001934; P:positive regulation of protein phosphorylation; IEA:Compara.
 GO:0032321; P:positive regulation of Rho GTPase activity; IEA:Compara.
 GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IEA:Compara.
 GO:0006457; P:protein folding; IEA:UniProtKB-KW.
 GO:0042127; P:regulation of cell proliferation; IEA:Compara.
 GO:0032465; P:regulation of cytokinesis; IEA:Compara.
 GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IEA:Compara. 

Interpro

 IPR000297; PPIase_PpiC.
 IPR023058; PPIase_PpiC_CS.
 IPR001202; WW_dom. 

Pfam

 PF00639; Rotamase
 PF00397; WW 

SMART

 SM00456; WW 

PROSITE

 PS01096; PPIC_PPIASE_1
 PS50198; PPIC_PPIASE_2
 PS01159; WW_DOMAIN_1
 PS50020; WW_DOMAIN_2 

PRINTS