UniProt Accession

 SH3L3_HUMAN; Q9H299; Q5T122 

Genbank Protein ID

 AJ297915; AF247790; AF304163; AL451139; BC030135 

Genbank Nucleotide ID

 CAC35770.1; AAL95695.1; AAG41412.1; CAI15827.1; AAH30135.1 

Protein Name

 SH3 domain-binding glutamic acid-rich-like protein 3 

Protein Synonyms/Alias

 SH3 domain-binding protein 1; SH3BP-1 

Gene Name

 SH3BGRL3 

Gene Synonyms/Alias

 P1725 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
18	VTGSREIKSQQSEVT	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Could act as a modulator of glutaredoxin biological activity. 

Sequence Annotation

 DOMAIN 1 93 Glutaredoxin.
 MOD_RES 2 2 N-acetylserine.  

Keyword

 3D-structure; Acetylation; Complete proteome; Cytoplasm; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 93 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 

Interpro

 IPR006993; Glut_rich_SH3-bd.
 IPR002109; Glutaredoxin.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF04908; SH3BGR 

SMART

  

PROSITE

 PS51354; GLUTAREDOXIN_2 

PRINTS