| Tag | Content |
|---|
| CPLM ID | CPLM-005365 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidyl-prolyl cis-trans isomerase CPR4 |
Protein Synonyms/Alias | PPIase CPR4; Rotamase |
Gene Name | CPR4 |
Gene Synonyms/Alias | CYP4; SCC3; YCR069W; YCR69W/YCR70W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 149 | DDENFYLKHDRPERL | ubiquitination | [1] | | 266 | ENIFRNDKAYTPLTT | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
Sequence Annotation | DOMAIN 55 225 PPIase cyclophilin-type.
CARBOHYD 166 166 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Glycoprotein; Isomerase; Membrane; Reference proteome; Rotamase; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 318 AA |
Protein Sequence | MWLKSLLLCL YSLVLCQVHA APSSGKQITS KDVDLQKKYE PSPPATHRGI ITIEYFDPVS 60
KSMKEADLTF ELYGTVVPKT VNNFAMLAHG VKAVIEGKDP NDIHTYSYRK TKINKVYPNK 120
YIQGGVVAPD VGPFTVYGPK FDDENFYLKH DRPERLAMAY FGPDSNTSEF IITTKADGNE 180
ELDGKSVVFG QITSGLDQLM DAIQYTETDE YGKPQHELRF LYFVLEILKI SNILDLHAAY 240
TEKVEKFRNG DVSVGSTLEN IFRNDKAYTP LTTSTGTTAY DLNHPISRAL MCLTVLGLCF 300
IAYKGMHEKP HTVSLRHK 318 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; ISS:SGD. GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; ISS:SGD. GO:0006457; P:protein folding; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |