UniProt Accession

 ANXA8_MOUSE; O35640; Q8K2N9 

Genbank Protein ID

 AJ002390; BC030407 

Genbank Nucleotide ID

 CAA05364.1; AAH30407.1 

Protein Name

 Annexin A8 

Protein Synonyms/Alias

 Annexin VIII; Annexin-8 

Gene Name

 Anxa8 

Gene Synonyms/Alias

 Anx8 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
222	RVFEEYEKIANKCIE	acetylation	[1]
267	ERLYYAMKGAGTRDG	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade (By similarity). 

Sequence Annotation

 REPEAT 38 90 Annexin 1.
 REPEAT 110 162 Annexin 2.
 REPEAT 195 247 Annexin 3.
 REPEAT 270 322 Annexin 4.
 METAL 266 266 Calcium; via carbonyl oxygen (By
 METAL 268 268 Calcium; via carbonyl oxygen (By
 METAL 270 270 Calcium; via carbonyl oxygen (By
 METAL 310 310 Calcium (By similarity).  

Keyword

 Annexin; Blood coagulation; Calcium; Calcium/phospholipid-binding; Complete proteome; Hemostasis; Metal-binding; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 327 AA 

Protein Sequence

Gene Ontology

 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.
 GO:0007596; P:blood coagulation; IEA:UniProtKB-KW. 

Interpro

 IPR001464; Annexin.
 IPR018502; Annexin_repeat.
 IPR018252; Annexin_repeat_CS.
 IPR009115; AnnexinVIII. 

Pfam

 PF00191; Annexin 

SMART

 SM00335; ANX 

PROSITE

 PS00223; ANNEXIN 

PRINTS

 PR00196; ANNEXIN.
 PR01808; ANNEXINVIII.