CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032635
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Replication factor C subunit, putative 
Protein Synonyms/Alias
  
Gene Name
 TGVEG_062100 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
13GDIRAFFKPKVPPPSacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1260 AA 
Protein Sequence
MDRKRGDIRA FFKPKVPPPS ASAAKETRRS VSTPEDPVLS QGAVRPGGSK QEEKIVNPGD 60
WTGRKEPVAQ QPAKPVQATD PGYERADDVA NQPVQLSSHG DSPDRIPKTS SMSQGRGKGG 120
RLRRIASSDD EDSSPRHSSC LRAGAPPPGS SLGKKVSPAV EVKRRPQNER GERREDAKSR 180
SKSKDVKQKA VEVVDVDDFF SSSVDKAVEK VLTRPPQKPT QSLQTEEMDV DEEDEEQEEK 240
AKERGEEEAK RSSCPGRLDR VASSPKGKRP ANTTSQWTKL VRSMEPEQVR QKRKKMEARQ 300
SPEVLSNSEE EMHARPRRPR QKDDEEEEYV ESSEEDEESE DDDADESEEE DTNGSLKAKG 360
RSKSHKEVQN PPSTAIARSP TAPSPSSARS WQAQQQKPEA MPAPAQQSST GKRMYTSNLE 420
EGSEQTSTCS PSPNRKKRKV EESVVPLTKK DKEEGSTNPL AGSTSCFAGK TFVFTGVLDS 480
MAREEAVSAV VGNGGRCTSA VSGRTDYLVA GALLEDGRDV TTGSKYRKAL QLMHDGKGKQ 540
KTSLKILHEQ EFLAMLPENA EKKPTLEARQ LQEETSRLES AKTVKSDGSA DEPDRQHSDE 600
NSGTLLWAEK YRPKRADDFV GNREHLRTLQ TWLADWADVC LHGIKKKPPP RSSAPSFSPY 660
GFAPTINLNA RAALLSGPPG IGKTTAARLA AEAAGYDVLE YNASDARNKA HIEDIGNMTS 720
GGLTLHSFLD QKNEASRGSP GRNAKRPMGA CVLMDEVDGL SGGDRGGAQA IVKLIETSKC 780
PIICICNDRM HPKVRTIASK CLDLRFHPPH MTALRSRVEK IAAAEDLSLD PQAVDYLCES 840
AGGDLRQILT SLQMIAYETR EKAKEKDWKS REEKADFSTG LKDEQVMHGP FECCKQLLDA 900
HQSSKLSRRQ KLDKFFSDYD LIPLLIQENY LEAFRQGMQR GSSPSAEKFS SPHTFSMTKK 960
TSLSSASSRV GVSTQPNDCF VINLVASAAC DLVEADIMNN VLRVSQQWGM LPDIGFLCCV 1020
SLPAKVEKAQ GFLGRVQFPS WLGRNSTQTK HKRLLTELLL VLLNQLQCCS TSSGLKLSGY 1080
LDALYRKCVG PLVRLSKADP KIAVEAAMQA MAEYSLTRGM VVDNLNSLRL KNQERLYDSI 1140
ETRVKSSFTR MCNAAAKASS AFIVEARKGR NAKAAAAEEE RQDGEQDMEV TTTGEDNVDA 1200
ADEDDDDPLR DSFILSAVKG KKEMKGAAGR SQRGGGPRST PRGESNAARR GKKVRSKAAT 1260 
Gene Ontology
 GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
 GO:0005663; C:DNA replication factor C complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0006260; P:DNA replication; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR001357; BRCT_dom.
 IPR008921; DNA_pol3_clamp-load_cplx_C.
 IPR010372; DNA_pol3_delta.
 IPR013725; DNA_replication_fac_RFC1_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA
 PF00533; BRCT
 PF06144; DNA_pol3_delta
 PF08519; RFC1 
SMART
 SM00382; AAA
 SM00292; BRCT 
PROSITE
 PS50172; BRCT 
PRINTS