CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041636
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Lamin-B1 
Protein Synonyms/Alias
 RCG46767, isoform CRA_c 
Gene Name
 Lmnb1 
Gene Synonyms/Alias
 rCG_46767 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
49RLAVYIDKVRSLETEacetylation[1]
79GRELTGLKALYETELacetylation[1]
102DTARERAKLQIELGKacetylation[1]
109KLQIELGKFKAEHDQacetylation[1]
111QIELGKFKAEHDQLLacetylation[1]
123QLLLNYAKKESDLSGacetylation[1]
134DLSGAQIKLREYEAAacetylation[1]
156LATALGDKKSLEGDLacetylation[1]
157ATALGDKKSLEGDLEacetylation[1]
157ATALGDKKSLEGDLEubiquitination[2]
181EASLSAAKKQLADETacetylation[1]
182ASLSAAKKQLADETLubiquitination[2]
241RQIEYEYKLAQALHEacetylation[1]
261DAQVRLYKEELEQTYacetylation[1]
271LEQTYHAKLENARLSacetylation[1]
312SQLSNLQKESRACLEacetylation[1]
330ELEDMLAKERDNSRRacetylation[1]
342SRRMLSDKEREMAEIacetylation[1]
483GDTSVSYKYTSRYVLacetylation[1]
528WGTGEDVKVVLKNSQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 587 AA 
Protein Sequence
MATATPVQQR AGSRASAPAT PLSPTRLSRL QEKEELRELN DRLAVYIDKV RSLETENSAL 60
QLQVTEREEV RGRELTGLKA LYETELADAR RALDDTARER AKLQIELGKF KAEHDQLLLN 120
YAKKESDLSG AQIKLREYEA ALNSKDAALA TALGDKKSLE GDLEDLKDQI AQLEASLSAA 180
KKQLADETLL KVDLENRCQS LTEDLEFRKN MYEEEINETR RKHETRLVEV DSGRQIEYEY 240
KLAQALHEMR EQHDAQVRLY KEELEQTYHA KLENARLSSE MNTSTVNSAR EELMESRMRI 300
ESLSSQLSNL QKESRACLER IQELEDMLAK ERDNSRRMLS DKEREMAEIR DQMQQQLNDY 360
EQLLDVKLAL DMEISAYRKL LEGEEERLKL SPSPSSRVTV SRASSSRSVR TTRGKRKRVD 420
VEESEASSSV SISHSASATG NVCIEEIDVD GKFIRLKNTS EQDQPMGGWE MIRKIGDTSV 480
SYKYTSRYVL KAGQTVTVWA ANAGVTASPP TDLIWKNQNS WGTGEDVKVV LKNSQGEEVA 540
QRSTVFKTTI PEEEEEEEEE PIGVAIEEER FHQQGTPRAS NKSCAIM 587 
Gene Ontology
 GO:0005638; C:lamin filament; IEA:Compara.
 GO:0005635; C:nuclear envelope; IEA:Compara.
 GO:0005654; C:nucleoplasm; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR018039; Intermediate_filament_CS.
 IPR001322; Lamin_tail_dom. 
Pfam
 PF00038; Filament
 PF00932; LTD 
SMART
  
PROSITE
 PS00226; IF 
PRINTS