CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014605
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Neutral and basic amino acid transport protein rBAT 
Protein Synonyms/Alias
 B(0,+)-type amino acid transport protein; NAA-TR; D2 
Gene Name
 Slc3a1 
Gene Synonyms/Alias
 Nbat 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
216IPNHTSDKHPWFQSSacetylation[1]
658KTLLHHQKAFRDKCFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule. 
Sequence Annotation
 CARBOHYD 211 211 N-linked (GlcNAc...) (Potential).
 CARBOHYD 238 238 N-linked (GlcNAc...) (Potential).
 CARBOHYD 258 258 N-linked (GlcNAc...) (Potential).
 CARBOHYD 329 329 N-linked (GlcNAc...) (Potential).
 CARBOHYD 510 510 N-linked (GlcNAc...) (Potential).
 CARBOHYD 520 520 N-linked (GlcNAc...) (Potential).
 CARBOHYD 574 574 N-linked (GlcNAc...) (Potential).  
Keyword
 Amino-acid transport; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 683 AA 
Protein Sequence
MNEDKDKRDS IQMSMKGCRT NNGFVQNEDI QEQDPDSRDT PQSNAVSIPA PEEPQLKVVR 60
PYAGMPKEVL FQFSGQARYR VPREILFWLT VVSVFLLIGA TIAIIIISPK CLDWWQAGPM 120
YQIYPRSFKD SDKDGNGDLK GIQEKLDYIT ALNIKTIWIT SFYKSPLKDF RYAVEDFKEI 180
DPIFGTMKDF ENLVAAVHDK GLKLIIDFIP NHTSDKHPWF QSSRTRSGKY TDYYIWHNCT 240
HANGVTTPPN NWLSVYGNSS WQFDEERKQC YFHQFLKEQP DLNFRNPAVQ EEIKEIIKFW 300
LSKGVDGFSF DAVKFLLEAK DLRNEIQVNT SQIPDTVTRY SELYHDFTTT QVGMHDLVRD 360
FRQTMNQFSR EPGRYRFMGT EVSAESTERT MVYYGLSFIQ EADFPFNKYL ATLDTLSGHT 420
VYEAITSWME NMPEGKWPNW MIGGPETSRL TSRVGSEYVN AMNMLLFTLP GTPITYYGEE 480
IGMGDISITN LNERYDTNAL LSKSPMQWDN SSNAGFTEAN HTWLPTNSDY HTVNVDVQKT 540
QPSSALRLYQ DLSLLHAREL LLSRGWFCLL RDDNHSVVYT RELDGIDKVF LVVLNFGESS 600
TVLNLQETIS DVPTKLRIRL STNPASKGSD VDTHAVSLEK GEGLILEHSM KTLLHHQKAF 660
RDKCFISNRA CYSSVLDLLY SSC 683 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IDA:RGD.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005774; C:vacuolar membrane; IDA:RGD.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0043169; F:cation binding; IEA:InterPro.
 GO:0046982; F:protein heterodimerization activity; IDA:RGD.
 GO:0006865; P:amino acid transport; IDA:RGD.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR015902; Glyco_hydro_13.
 IPR006047; Glyco_hydro_13_cat_dom.
 IPR006589; Glyco_hydro_13_sub_cat_dom.
 IPR013781; Glyco_hydro_catalytic_dom.
 IPR017853; Glycoside_hydrolase_SF. 
Pfam
 PF00128; Alpha-amylase 
SMART
 SM00642; Aamy 
PROSITE
  
PRINTS