| Tag | Content |
|---|
| CPLM ID | CPLM-014954 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Keratin, type II cytoskeletal 7 |
Protein Synonyms/Alias | Cytokeratin-7; CK-7; Keratin-7; K7; Type-II keratin Kb7 |
Gene Name | Krt7 |
Gene Synonyms/Alias | Kb7; Krt2-7 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 325 | TLKNQRAKLESSIAE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Blocks interferon-dependent interphase and stimulates DNA synthesis in cells (By similarity). |
Sequence Annotation | REGION 2 84 Head.
REGION 84 120 Coil 1A.
REGION 85 393 Rod.
REGION 121 138 Linker 1.
REGION 139 230 Coil 1B.
REGION 231 254 Linker 12.
REGION 255 393 Coil 2.
REGION 394 457 Tail.
MOD_RES 2 2 N-acetylserine (By similarity).
MOD_RES 2 2 Phosphoserine (By similarity).
MOD_RES 15 15 Dimethylated arginine; alternate (By
MOD_RES 15 15 Omega-N-methylarginine; alternate (By
MOD_RES 173 173 N6-acetyllysine (By similarity).
MOD_RES 246 246 Phosphoserine (By similarity).
MOD_RES 248 248 Phosphoserine (By similarity). |
Keyword | Acetylation; Coiled coil; Complete proteome; Intermediate filament; Keratin; Methylation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 457 AA |
Protein Sequence | MSIHFSSRST AYPGRGAQVR LSSGRASFGS RSLYGLGSSR PRVAVRSAYG GPVGAGIREI 60
TINQSLLAPL SVDIDPTIQQ VRQEEREQIK TLNNKFASFI DKVRFLEQQN KMLETKWALL 120
QEQKSAKSSQ LPRIFEAQIA GLRQQLETLQ LDGGRLEVEL RNMQDVVEDF KNKYEEEINR 180
RTAAENEFVL LKKDVDAAYT NKVELEAKAD SLQDEINFLK TLHETELAEL QSQISDTSVV 240
LSMDNSRSLD LDGIIADVKA QYEEMANHSR AEAEAWYQTK FETLQAQAGK HGDDLRNTRN 300
EIAEMNRSIQ RLQAEIDTLK NQRAKLESSI AEAEEQGELA IKDAHAKQGE LEAALQKAKQ 360
DVARQLREYQ ELLNTKLALD IEIATYRKLL EGEESRLSGD GMGPVNISVV NSTGGNGGKL 420
IFGGTMGSNA LSFSGGPGAL RAYSIKTTST TRRGTHN 457 |
Gene Ontology | GO:0045095; C:keratin filament; IEA:InterPro. GO:0005198; F:structural molecule activity; IEA:InterPro. GO:0006417; P:regulation of translation; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |