| Tag | Content |
|---|
| CPLM ID | CPLM-001837 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Threonine dehydratase, mitochondrial |
Protein Synonyms/Alias | Threonine deaminase |
Gene Name | ILV1 |
Gene Synonyms/Alias | YER086W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 51 | IKLHSELKLDELQTD | acetylation | [1] | | 191 | EAKAECAKLAEERGL | acetylation | [1] | | 490 | YLVGGASKVPNERII | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | |
Sequence Annotation | DOMAIN 393 473 ACT-like 1.
DOMAIN 495 566 ACT-like 2.
MOD_RES 109 109 N6-(pyridoxal phosphate)lysine (By |
Keyword | Allosteric enzyme; Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Isoleucine biosynthesis; Lyase; Mitochondrion; Pyridoxal phosphate; Reference proteome; Repeat; Transit peptide. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 576 AA |
Protein Sequence | MSATLLKQPL CTVVRQGKQS KVSGLNLLRL KAHLHRQHLS PSLIKLHSEL KLDELQTDNT 60
PDYVRLVLRS SVYDVINESP ISQGVGLSSR LNTNVILKRE DLLPVFSFKL RGAYNMIAKL 120
DDSQRNQGVI ACSAGNHAQG VAFAAKHLKI PATIVMPVCT PSIKYQNVSR LGSQVVLYGN 180
DFDEAKAECA KLAEERGLTN IPPFDHPYVI AGQGTVAMEI LRQVRTANKI GAVFVPVGGG 240
GLIAGIGAYL KRVAPHIKII GVETYDAATL HNSLQRNQRT PLPVVGTFAD GTSVRMIGEE 300
TFRVAQQVVD EVVLVNTDEI CAAVKDIFED TRSIVEPSGA LSVAGMKKYI STVHPEIDHT 360
KNTYVPILSG ANMNFDRLRF VSERAVLGEG KEVFMLVTLP DVPGAFKKMQ KIIHPRSVTE 420
FSYRYNEHRH ESSSEVPKAY IYTSFSVVDR EKEIKQVMQQ LNALGFEAVD ISDNELAKSH 480
GRYLVGGASK VPNERIISFE FPERPGALTR FLGGLSDSWN LTLFHYRNHG ADIGKVLAGI 540
SVPPRENLTF QKFLEDLGYT YHDETDNTVY QKFLKY 576 |
Gene Ontology | GO:0005739; C:mitochondrion; IDA:SGD. GO:0004794; F:L-threonine ammonia-lyase activity; IMP:SGD. GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro. GO:0009097; P:isoleucine biosynthetic process; IMP:SGD. GO:0006567; P:threonine catabolic process; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |