CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024304
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein lin-54 homolog 
Protein Synonyms/Alias
 Myb complex protein of 120 kDa 
Gene Name
 mip120 
Gene Synonyms/Alias
 CG6061 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
268VVRTADGKIIKINQAacetylation[1]
314TGNVVLNKPVGQVVVacetylation[1]
351MLVQSGGKQILVSNKacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In follicle cells, the complex plays a central role in the site-specific DNA replication at the chorion loci. During development, the complex represses transcription of developmentally controlled E2F target genes. 
Sequence Annotation
 DOMAIN 737 849 CRC.  
Keyword
 Activator; Alternative splicing; Cell cycle; Complete proteome; DNA-binding; Nucleus; Reference proteome; Repressor; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 950 AA 
Protein Sequence
MDTSGGNLDS LDDTEPLPEL SFEDFLEPTS EKSSQHMEIE ALDSEEDNIG GEDLADPAND 60
SLNTPQFKKN VVHILEDKRL NSSGLTVLKS HAIKMVTAGG TPPAKAQVTD VKILNKLKPI 120
PSSTLKIGST TIATKSTPGS ITKTLGNLTQ IRTKDGQVIF VQKSVPGTQS STAVTGSPSG 180
GIRRLVAPSG IQKAVLSKGV TMASTGLVKA AVPAKASTSV PGSAITLKGI QPLAGGTAKA 240
STSSTTATTS PSLAQPNKIQ VVRTADGKII KINQAGPSLL VNAKQGTGTT VTPGGSAATS 300
VKLSPSTGNV VLNKPVGQVV VRTETPVKTA TGSVASASAT PGKMLVQSGG KQILVSNKNI 360
IKLSPNASAT SSTTHTTGGQ TPSTSSGLHA IQLPGKGGIQ YVRVLNNNKS AAGTSATASI 420
PKTVQTQKIT VVRPPAATGV PATSTTTSAA AASPAAASKA NLAMGNTNKI VMRSMGGSIV 480
PLPSVQTLVS KRALGAISNA SKPASAASSS ATPSASQELP RKHRLTDLNV QLKQSASVSS 540
EASDSSDAGP EAKKPRYVIT MQQGSQKAAS QPVQKLINRT ANVQRVVSSS TSPSSNSTKK 600
IYNYVQPTGS NGAKYMICNS GVPQSSTSAM RRGYTGYVEN KTRRPPPISP QQHRFKQMGP 660
QQQSKHQQLQ AQAKQRIRQQ QLPTEQSTPI KVEPKLPTLP PGVKANVPAK PLFEVLKPPA 720
TAAAAGAVDP LGGMTSRRKH CNCSKSQCLK LYCDCFANGE FCQDCTCKDC FNNLDYEVER 780
ERAIRSCLDR NPSAFKPKIT APNSGDMRLH NKGCNCKRSG CLKNYCECYE AKIPCSSICK 840
CVGCRNMEDR PDVDMDSLDG LMGVEGQKKD KAKNKQLNEN RANIYFTDDV IEATIMCMIS 900
RIVMHEKQNV AVEDMEREVM EEMGESLTQI IAFAKEKQET SQIDESKPSS 950 
Gene Ontology
 GO:0000785; C:chromatin; IDA:FlyBase.
 GO:0031523; C:Myb complex; IDA:FlyBase.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005700; C:polytene chromosome; IDA:FlyBase.
 GO:0003677; F:DNA binding; IDA:FlyBase.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0008340; P:determination of adult lifespan; IMP:FlyBase.
 GO:0007307; P:eggshell chorion gene amplification; IC:FlyBase.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.
 GO:0030317; P:sperm motility; IMP:FlyBase.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR005172; CRC. 
Pfam
 PF03638; CXC 
SMART
  
PROSITE
 PS51634; CRC 
PRINTS