CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011417
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosomal RNA-processing protein 9 
Protein Synonyms/Alias
  
Gene Name
 RRP9 
Gene Synonyms/Alias
 YPR137W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
290VLSLAFRKNSDQLYAubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Involved in nucleolar processing of pre-18S ribosomal RNA. Required for efficient pre-rRNA cleavage at sites A0, A1 and A2, and biosynthesis of 18S rRNA. 
Sequence Annotation
 REPEAT 234 273 WD 1.
 REPEAT 278 317 WD 2.
 REPEAT 320 359 WD 3.
 REPEAT 397 435 WD 4.
 REPEAT 471 509 WD 5.
 REPEAT 516 562 WD 6.
 MOD_RES 50 50 Phosphoserine.  
Keyword
 3D-structure; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 573 AA 
Protein Sequence
MSDVTQQKKR KRSKGEVNPS KPTVDEEITD PSSNEDEQLE VSDEEDALES EEEFEGENPA 60
DKRRRLAKQY LENLKSEAND ILTDNRNAEE KDLNNLKERT IDEYNNFDAG DLDKDIIASR 120
LKEDVAEQQG RVFRYFGDKL LISEAKQSFT RVGENNLTCI SCFQPVLNKY TFEESSNGDK 180
NKGRLFAYTV SKDLQLTKYD ITDFSKRPKK LKYAKGGAKY IPTSKHEYEN TTEGHYDEIL 240
TVAASPDGKY VVTGGRDRKL IVWSTESLSP VKVIPTKDRR GEVLSLAFRK NSDQLYASCA 300
DFKIRTYSIN QFSQLEILYG HHDIVEDISA LAMERCVTVG ARDRTAMLWK IPDETRLTFR 360
GGDEPQKLLR RWMKENAKEG EDGEVKYPDE SEAPLFFCEG SIDVVSMVDD FHFITGSDNG 420
NICLWSLAKK KPIFTERIAH GILPEPSFND ISGETDEELR KRQLQGKKLL QPFWITSLYA 480
IPYSNVFISG SWSGSLKVWK ISDNLRSFEL LGELSGAKGV VTKIQVVESG KHGKEKFRIL 540
ASIAKEHRLG RWIANVSGAR NGIYSAVIDQ TGF 573 
Gene Ontology
 GO:0030686; C:90S preribosome; IDA:SGD.
 GO:0031428; C:box C/D snoRNP complex; IDA:SGD.
 GO:0032040; C:small-subunit processome; IDA:SGD.
 GO:0030515; F:snoRNA binding; IPI:SGD.
 GO:0000154; P:rRNA modification; TAS:SGD. 
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS