UniProt Accession

 CD48_RAT; P10252 

Genbank Protein ID

 X13016; BC060542 

Genbank Nucleotide ID

 CAA31438.1; AAH60542.1 

Protein Name

 CD48 antigen 

Protein Synonyms/Alias

 BCM1 surface antigen; BLAST-1; MRC OX-45 surface antigen; SLAM family member 2; SLAMF2; Signaling lymphocytic activation molecule 2; CD48 

Gene Name

 Cd48 

Gene Synonyms/Alias

 Bcm-1 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
88	KDRVDLDKTNGALRI	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation. 

Sequence Annotation

 DOMAIN 29 127 Ig-like C2-type 1.
 DOMAIN 131 207 Ig-like C2-type 2.
 LIPID 217 217 GPI-anchor amidated serine (Potential).
 CARBOHYD 38 38 N-linked (GlcNAc...).
 CARBOHYD 97 97 N-linked (GlcNAc...).
 CARBOHYD 140 140 N-linked (GlcNAc...).
 CARBOHYD 186 186 N-linked (GlcNAc...) (Potential).
 CARBOHYD 203 203 N-linked (GlcNAc...) (Potential).  

Keyword

 3D-structure; Cell membrane; Complete proteome; Glycoprotein; GPI-anchor; Immunoglobulin domain; Lipoprotein; Membrane; Reference proteome; Repeat; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 240 AA 

Protein Sequence

Gene Ontology

 GO:0046658; C:anchored to plasma membrane; IDA:RGD.
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0003823; F:antigen binding; IMP:RGD.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0045576; P:mast cell activation; IMP:RGD.
 GO:0007165; P:signal transduction; IEA:Compara.
 GO:0042110; P:T cell activation; IEA:Compara. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR013106; Ig_V-set.
 IPR015631; SLAM_fam_rcpts. 

Pfam

 PF07686; V-set 

SMART

 SM00409; IG 

PROSITE

 PS50835; IG_LIKE 

PRINTS