CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG142264, isoform CRA_b 
Protein Synonyms/Alias
 Protein Akr1b10 
Gene Name
 Akr1b10 
Gene Synonyms/Alias
 mCG_142264 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
173QIERLLNKPGLKHKPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 ACT_SITE 49 49 Proton donor (By similarity).  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 316 AA 
Protein Sequence
MAAFVTLLTG AKMPIVGLGT WKSPPAKVRE AVKVAIDAGY RHIDCAYVYQ NESEVGEAIQ 60
EKIQEKAVKR EDLFIVSKLW STFFEKSLVK KAFQNTLSDL KLDYLDLYLI HWPQGFQSGN 120
VFLPTDDKGS ILSSKYTFLD AWEAMEELVD QGLVKALGVS NFNHFQIERL LNKPGLKHKP 180
VTNQVECHPY LTQEKLIQYC HSKGITITAY SPLGSPDRPS AKPEDPLLLE IPKIKEIAAK 240
HKRTAAQVLI RFHIERNVVV IPKSVTPSRI QENIQVFDFQ LSEEDMAAIL SFNRNWRACG 300
LFAASHNEDF PFHAEY 316 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 
Interpro
 IPR001395; Aldo/ket_red.
 IPR018170; Aldo/ket_reductase_CS.
 IPR020471; Aldo/keto_reductase_subgr.
 IPR023210; NADP_OxRdtase_dom. 
Pfam
 PF00248; Aldo_ket_red 
SMART
  
PROSITE
 PS00798; ALDOKETO_REDUCTASE_1
 PS00062; ALDOKETO_REDUCTASE_2
 PS00063; ALDOKETO_REDUCTASE_3 
PRINTS
 PR00069; ALDKETRDTASE.