CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Diacylglycerol kinase eta 
Protein Synonyms/Alias
  
Gene Name
 DGKH 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
287KVEKTYDKTLENAVVubiquitination[1]
301VADAVASKCSVLNEKubiquitination[1]
577ELLQRSYKNLEQRVQubiquitination[1]
788ACSHALNKANPRCPEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 919 AA 
Protein Sequence
MWNISQGCTT GTPAPTPDPP SVTCAERVFL ESPPMACPAK VHTACKDLYH PICPLGQCKV 60
SIIPPIALNS TDSDGFCRAT FSFCVSPLLV FVNSKSGDNQ GVKFLRRFKQ LLNPAQVFDL 120
MNGGPHLGLR LFQKFDNFRI LVCGGDGSVG WVLSEIDKLN LNKQCQLGVL PLGTGNDLAR 180
VLGWGGSYDD DTQLPQILEK LERASTKMLD RWSIMTYELK LPPKASLLPG PPEASEEFYM 240
TIYEDSVATH LTKILNSDEH AVVISSAKTL CETVKDFVAK VEKTYDKTLE NAVVADAVAS 300
KCSVLNEKLE QLLQALHTDS QAAPVLPGLS PLIVEEDAVE SSSEESLGES KEQLGDDVTK 360
PSSQKAVKPR EIMLRANSLK KAVRQVIEEA GKVMDDPTVH PCEPANQSSD YDSTETDESK 420
EEAKDDGAKE SITVKTAPRS PDARASYGHS QTDSVPGPAV AASKENLPVL NTRIICPGLR 480
AGLAASIAGS SIINKMLLAN IDPFGATPFI DPDLDSVDGY SEKCVMNNYF GIGLDAKISL 540
EFNNKREEHP EKCRSRTKNL MWYGVLGTRE LLQRSYKNLE QRVQLECDGQ YIPLPSLQGI 600
AVLNIPSYAG GTNFWGGTKE DDIFAAPSFD DKILEVVAIF DSMQMAVSRV IKLQHHRIAQ 660
CRTVKITIFG DEGVPVQVDG EAWVQPPGII KIVHKNRAQM LTRDRAFEST LKSWEDKQKC 720
DSGKPVLRTH LYIHHAIDLA TEEVSQMQLC SQAAEELITR ICDAATIHCL LEQELAHAVN 780
ACSHALNKAN PRCPESLTRD TATEIAINVK ALYNETESLL VGRVPLQLES PHEERVSNAL 840
HSVEVELQKL TEIPWLYYIL HPNEDEEPPM DCTKRNNRST VFRIVPKFKK EKVQKQKTSS 900
QPGSGDTESG SCEANSPGN 919 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom. 
Pfam
 PF00609; DAGK_acc
 PF00781; DAGK_cat 
SMART
 SM00045; DAGKa
 SM00046; DAGKc 
PROSITE
 PS50146; DAGK 
PRINTS