CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039751
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Neural cell adhesion molecule L1 
Protein Synonyms/Alias
  
Gene Name
 L1CAM 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
146KWPKETVKPVEVEEGubiquitination[1]
182NSKILHIKQDERVTMubiquitination[1]
303NKTLQLLKVGEEDDGubiquitination[1]
380IPVEELAKDQKYRIQubiquitination[1]
696FRVTAINKYGPGEPSubiquitination[1]
844PVDLAQVKGHLRGYNubiquitination[1]
1000FQLQATTKEGPGEAIubiquitination[1]
1158GKYSVKDKEDTQVDSubiquitination[2]
1171DSEARPMKDETFGEYubiquitination[2]
Reference
 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1259 AA 
Protein Sequence
MVVALRYVWP LLLCSPCLLI QIPEESFPGH RVVMEPPVIT EQSPRRLVVF PTDDISLKCE 60
ASGKPEVQFR WTRDGVHFKP KEELGVTVYQ SPHSGSFTIT GNNSNFAQRF QGIYRCFASN 120
KLGTAMSHEI RLMAEGAPKW PKETVKPVEV EEGESVVLPC NPPPSAEPLR IYWMNSKILH 180
IKQDERVTMG QNGNLYFANV LTSDNHSDYI CHAHFPGTRT IIQKEPIDLR VKATNSMIDR 240
KPRLLFPTNS SSHLVALQGQ PLVLECIAEG FPTPTIKWLR PSGPMPADRV TYQNHNKTLQ 300
LLKVGEEDDG EYRCLAENSL GSARHAYYVT VEAAPYWLHK PQSHLYGPGE TARLDCQVQG 360
RPQPEVTWRI NGIPVEELAK DQKYRIQRGA LILSNVQPSD TMVTQCEARN RHGLLLANAY 420
IYVVQLPAKI LTADNQTYMA VQGSTAYLLC KAFGAPVPSV QWLDEDGTTV LQDERFFPYA 480
NGTLGIRDLQ ANDTGRYFCL AANDQNNVTI MANLKVKDAT QITQGPRSTI EKKGSRVTFT 540
CQASFDPSLQ PSITWRGDGR DLQELGDSDK YFIEDGRLVI HSLDYSDQGN YSCVASTELD 600
VVESRAQLLV VGSPGPVPRL VLSDLHLLTQ SQVRVSWSPA EDHNAPIEKY DIEFEDKEMA 660
PEKWYSLGKV PGNQTSTTLK LSPYVHYTFR VTAINKYGPG EPSPVSETVV TPEAAPEKNP 720
VDVKGEGNET TNMVITWKPL RWMDWNAPQV QYRVQWRPQG TRGPWQEQIV SDPFLVVSNT 780
STFVPYEIKV QAVNSQGKGP EPQVTIGYSG EDYPQAIPEL EGIEILNSSA VLVKWRPVDL 840
AQVKGHLRGY NVTYWREGSQ RKHSKRHIHK DHVVVPANTT SVILSGLRPY SSYHLEVQAF 900
NGRGSGPASE FTFSTPEGVP GHPEALHLEC QSNTSLLLRW QPPLSHNGVL TGYVLSYHPL 960
DEGGKGQLSF NLRDPELRTH NLTDLSPHLR YRFQLQATTK EGPGEAIVRE GGTMALSGIS 1020
DFGNISATAG ENYSVVSWVP KEGQCNFRFH ILFKALGEEK GGASLSPQYV SYNQSSYTQW 1080
DLQPDTDYEI HLFKERMFRH QMAVKTNGTG RVRLPPAGFA TEGWFIGFVS AIILLLLVLL 1140
ILCFIKRSKG GKYSVKDKED TQVDSEARPM KDETFGEYRS LESDNEEKAF GSSQPSLNGD 1200
IKPLGSDDSL ADYGGSVDVQ FNEDGSFIGQ YSGKKEKEAA GGNDSSGATS PINPAVALE 1259 
Gene Ontology
  
Interpro
 IPR026966; Fibronectin_III_C.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 
Pfam
 PF13882; Bravo_FIGEY
 PF00041; fn3
 PF07679; I-set 
SMART
 SM00060; FN3
 SM00409; IG
 SM00408; IGc2 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE 
PRINTS