CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026886
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ferritin 
Protein Synonyms/Alias
  
Gene Name
 FTL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68EGYERLLKMQNQRGGubiquitination[1]
83RALFQDIKKPAEDEWubiquitination[1]
84ALFQDIKKPAEDEWGubiquitination[1]
92PAEDEWGKTPDAMKAubiquitination[1]
98GKTPDAMKAAMALEKubiquitination[1]
105KAAMALEKKLNQALLubiquitination[1]
106AAMALEKKLNQALLDubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity). 
Sequence Annotation
  
Keyword
 Iron; Iron storage; Metal-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 191 AA 
Protein Sequence
MSSQIRQNYS TDVEAAVNSL VNLYLQASYT YLSLGFYFDR DDVALEGVSH FFRELAEEKR 60
EGYERLLKMQ NQRGGRALFQ DIKKPAEDEW GKTPDAMKAA MALEKKLNQA LLDLHALGSA 120
RTDPHLCDFL ETHFLDEEVK LIKKMGDHLT NLHRLGGPEA GLGEYLSSKG SLSSTTKSLL 180
SPATSEGPLA K 191 
Gene Ontology
 GO:0008199; F:ferric iron binding; IEA:InterPro.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0006879; P:cellular iron ion homeostasis; IEA:UniProtKB-KW.
 GO:0006826; P:iron ion transport; IEA:InterPro. 
Interpro
 IPR001519; Ferritin.
 IPR009040; Ferritin-like_diiron.
 IPR009078; Ferritin-like_SF.
 IPR012347; Ferritin-rel.
 IPR014034; Ferritin_CS.
 IPR008331; Ferritin_DPS_dom. 
Pfam
 PF00210; Ferritin 
SMART
  
PROSITE
 PS00540; FERRITIN_1
 PS00204; FERRITIN_2
 PS50905; FERRITIN_LIKE 
PRINTS