CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016645
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar protein sorting-associated protein 13C 
Protein Synonyms/Alias
  
Gene Name
 Vps13c 
Gene Synonyms/Alias
 Kiaa3021 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
577QALKIEAKLEHWYVTubiquitination[1]
2072QSPENIAKEIQIPSRubiquitination[1]
2150EASVRDLKVLACPFLubiquitination[1]
2422DRAPFTVKNALGVPMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 MOD_RES 613 613 Phosphothreonine (By similarity).
 MOD_RES 618 618 Phosphoserine (By similarity).
 MOD_RES 623 623 Phosphothreonine (By similarity).
 MOD_RES 736 736 Phosphoserine (By similarity).
 MOD_RES 1435 1435 Phosphothreonine.
 MOD_RES 1968 1968 Phosphothreonine.
 MOD_RES 1974 1974 Phosphoserine.
 MOD_RES 3533 3533 N6-acetyllysine (By similarity).
 CROSSLNK 2352 2352 Glycyl lysine isopeptide (Lys-Gly)  
Keyword
 Acetylation; Alternative splicing; Complete proteome; Isopeptide bond; Phosphoprotein; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3748 AA 
Protein Sequence
MVLESVVADL LNRFLGDYVE NLNKSQLKLG IWGGNVALDN LQIKENALSE LDVPFKVKAG 60
QIDKLTLKIP WKNLYGEAVV ATLEGLYLLV VPGASIKYDA EKEEKSLQDI KQKELCRIEE 120
ALQKAAEKGA HSGEFMYGLE NLLYKDVKPG RKRKKHKKHF KKRFKGLDRS KDKPKEAKKD 180
TFLEKLATQV IKNVQVKITD IHIKYEDDIT DPERPLSFGV TLREFSLLTT NEHWTPCILN 240
EAEKIIYKLV KLDSLSAYWN VGCCMSYRGS REHILEQLKR EILTSTNIPP DHQYIFQPIS 300
ASAKLYMNPG AESELKTPKL DGNVEVQNIA IELTKPQYLS MIDFLESLDY MVRNAPYRKY 360
KPCLPLHTNC RQWWKYAIDS VLEVHIRRYT QPWSWSNIKN HRQLLKSYKM AYKTKLTQAK 420
VSEEIQKQIQ DLEKSLDVFN IILVRQQAQV EVIHSGQKLR KKSAEAGEKR GWFSGFWGKK 480
ESKKRDEESS VPETIDDLMT PEEKDKLFTA IGYSENAYNL ALPKQYVAHI LTLKLVSTSI 540
IIRENRNVPE ILRVQIIGLG TQVSQRPGAQ ALKIEAKLEH WYVTGLRQQD IVPSLVASIG 600
DTTSSLLKIE FETNPENSPA DQTLIVQSQP VEVIYDAKTI NAVVEFFQSN KGLDLEQITS 660
ATLMKLEEIK ERTATGLTHI IETRKVLDLR INLKPSYLII PQTGFHHEKS NLLILDFGTF 720
QLNSKDQGAQ KTANASLEEI IDKAYDKFDV EIRSVQLLFA KAEENWKKCR FQHPSTMHIL 780
QPMDIHVELA KAMVEKDVRM AKFKVSGGLP LMHVRISDQK IKDALCLINS IPLPQKSSTP 840
SPERQVASIP VLSGGTKALL GTSLLLDGVE SESDEEFFDA EDGDSQAART VKASELKKAA 900
EVPNEELVSL LLKFEIKEVV LELTKQQKEE ETILVFNVTQ LGTEATMRTF DLTAVSYLRK 960
ISLDYHDIKG SRKKPIHLIS SSDRPGLDLL KVEYIKVDRN GPSFQTTFEK TEQTVKVAFS 1020
SLNLLLQTQA LLSSLNYLTT VIPSDSQNTG VAKEVQAMPE KQKNSPLQKV MVPSRDSDVI 1080
GFRLFAKLNA FCVTVCDEKS NIAEIKIQGL DSSLSLQSKK QSLFARLENI IVTDVDPKTI 1140
HKKAVSIVGN EVFRFNLDLY PDATEGDSYT DMSTVDGVVA LHVGCIQIVY LHKFLMSLLS 1200
FLNNFQVAKE ALSAATAQAA EKAATSVKDL AQRSFRVSVD IDLKAPVIVI PQSSLSTNAV 1260
VVDLGLIRVH NRFSLVSGED TANPPVIDKM EVQLTKLKLS RTAIQPGTSH PDIQLLHPIN 1320
LEFFVSRNLA ANWYHKVPVV EIKGRLDSMN VSLNQEDLNL LFRILAENLG EATEDLDKGK 1380
PRIQERGETK ACREVSTPQD VHTTQGVPAA RVEETRPVDI INVLLNFEIK EVVVTLMKKA 1440
ERKGSPFHEL KILHLGMEAK VKAHDMTAAA YLRNISMRCF HFPDSKGEPL RIVNTSDVSD 1500
GILLKLLFIK ADSDGPDFKT IHDNTKQKLK VSFSSLDLVL HLEALLSLMD FLSSAIPSSD 1560
SSSSEKEPEL KPLVGESRSL AIRAVPSSYE GDAFDLKITA ELNAFNIFIC DQKSNIAEIK 1620
IHGMDASISV KPKQTDVFAR LKNIIVMNVD SLSIHKKAVS ILGDEVFRFQ MSLYPDATEG 1680
ENYGDMSKVD GRLSLKVGCI QIVYVHKFFM SLLSFLNNFQ AAKEALSTAT VQAAERAASS 1740
VKDLAQKSFR LLMDIDLKAP VITIPQSSVS PNVVIADLGL IRVENKFSLV SVEQLALPPV 1800
ADEMSIQLTQ LKLARTVLQA DSPQHDVEIL KPVNMLLCIQ RNLSAAWYTQ IPGMEIKGEL 1860
KPMQVALSQD DLTVLMKILL ENLGEASSQP SPTQYAQEAA RVKRDTRSGP DYLKEQELAD 1920
PKPPGDQTVT LQFDFHFDSL SIILYNSDSS QEPRLSFHND SFRLGELTLH LMASAGKMFK 1980
DGSMNVSLKL KTCTLDDLRE GIERATSRMI DKKNDQDNNS SMIDISYSQD KNGSQVDAVL 2040
DKLYVCASVE FLMTVADFFI KAMPQSPENI AKEIQIPSRQ TAAGRVKMEK DDSVRPNMTL 2100
KAMITDPEVV FVASLTKADA PALTASFQCN LSLSTSKLEQ MMEASVRDLK VLACPFLRER 2160
RGKSITTVLQ PCSLFMEKCT WASGKQNINI VVKEFVIKIS PIILNTVMTI MAAMSPKTKE 2220
DEWKDTPKET DNLWAVKSIT DYNSWFLGVD MATEVTENFR DSEHPSIEEN CVVAVESVQV 2280
TLECGLGHRT VPLLLAESKF SGNIKNWTSL MAAAADMTLE VHYYNETHAV WEPLIERVEG 2340
NKPWSLKLNV KKNPIQDKSL MPGDDFIPEP QTAVHISSGA TMNITISKSC LNVFSNLAKG 2400
FSEGAASTFD YSLKDRAPFT VKNALGVPMK VQPNRNLKVM GSPEKSDIYD VGAGQHLELD 2460
YASLEPSRQG KLSILSRQES SLFTLTFVPY GYTEVASVPV ARPGRRLYNV RNPSASHSDS 2520
VLVQIDATEG NKVVTLRSPL QIKNHFSIAF IIYKFVKNVK LLERIGIARP EEEFHVPLDS 2580
YRCQLYVQPA GGLEQQYTHS STYISWKEEL HRSREVRCML QCPAVEVSFL PLIVNTVALP 2640
DELSYIGAHG EDWDPAYVIH LYPPLTLRNL LPYSLRYLLE GTAETHELAE GSSADVLHSR 2700
ISGEIIELVL VKYLGKNWNG HFRICDTLPE FFLVCFSSDT AEVMTVDLSV HVRRIGCRME 2760
LSVFSPYWLI NKTSRVLQYR SEEIHVKHPA DFRDIILFSF KKKNIFSKNK VQLKISTSAW 2820
SNGFSLDTVG SYGCVKCPAT NMEYLVGVSI KMSSFNLSRV VTLTPFCTVA NKSSLDLEVG 2880
EIASDGSIPT NKWHYVASSE CIPFWPENLS GKLCVRVVGY EGSSKPFFYN RQDNGTLLSL 2940
EDLNGGILVD INTAEHSTVI TFSDYHEGSA PALIMNHTQW DVLTYKQSGS QEELVLLPGE 3000
TRLFAWADPT GIRKLTWNYA ANFGEHDLLK DECGQFPYDA NIQIHWVSFL DGRQRVLLFT 3060
DDVALVSKAL QAEEMEQADH EVALSLHSLG LSLVNNENKQ EVSYVGITSS GVVWEMKPKQ 3120
KWKPFSQKQI MSLEQAYSKR LASQDRGWVK LDSNFEVNFD KVPMEMRLPI RCPIKRDFLS 3180
GIQVEFKQSP HQRSLRARLY WLQVDNQLPG TMFPVVFHPV APPKSIALDS EPKPFIDVSV 3240
ITRFNEYSKV LQFKYFMVLI QEMALKVDQG FLGAVISLFT PTTDPEAERK RTKLIQQDID 3300
ALNTELMESS MTDMSILSFF EHFHISPVKL HLSLSLGSGG EESDKEKQEM IAIHSVNLLL 3360
KSIGATLTDV DDLIFKLAYY EIRYQFYKRD QLMWSVVRHY SEQFLKQMYV LVLGLDVLGN 3420
PFGLIRGLSE GVEALFYEPF QGAVQGPEEF AEGLVIGVRS LVGHTVGGAA GVVSRITGSV 3480
GKGLAAITMD KEYQQKRREE MGRQPKDFGD SLARGGKGFL RGVVGGVTGI ITKPVEGAKK 3540
EGAAGFFKGI GKGLVGAVAR PTGGIIDMAS STFQGIQRVA ESTEEVSSLR PPRLIHEDGI 3600
IRPYDRQESE GSDLLENHIK KLEGEAYQFH CAVPGNKRAV LMITNRRALF IKEVEILGHM 3660
SVDWQCLFED FVCPPEVSEN LLKISVKEQG LFHKKDSANI GHLRKIYLKD PITAKRAFDA 3720
IESAQSARQQ QKLMRQSSVK LLRPQGPS 3748 
Gene Ontology
  
Interpro
 IPR015412; Autophagy-rel_C.
 IPR026847; VPS13.
 IPR026854; VPS13A_N.
 IPR009543; VPSAP_dom. 
Pfam
 PF09333; ATG_C
 PF12624; Chorein_N
 PF06650; DUF1162 
SMART
  
PROSITE
  
PRINTS