CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036144
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 BRCA1-A complex subunit RAP80 
Protein Synonyms/Alias
  
Gene Name
 UIMC1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
147SVAALTSKRSLVLMPubiquitination[1]
199VRIIMADKEVGNKEDubiquitination[2, 3]
204ADKEVGNKEDAEKEVubiquitination[1, 2, 4]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 255 AA 
Protein Sequence
MPRRKKKVKE VSESRNLEKK DVETTSSVSV KRKRRLEDAF IVISDSDGEE PKEENGLQKT 60
KTKQSNRAKC LAKRKIAQMT EEEQFALALK MSEQEAREVN SQEEEEEELL RKAIAESLNS 120
SQGIVEETSE EGNSVPASQS VAALTSKRSL VLMPESSAEE ITVCPETQLS SSETFDLERE 180
VSPGSRDILD GVRIIMADKE VGNKEDAEKE VAISTFSSSN QVSCPLCDQC FPPTKIERHA 240
MYCNGLMEED TGKDY 255 
Gene Ontology
  
Interpro
 IPR003903; Ubiquitin-int_motif. 
Pfam
  
SMART
 SM00726; UIM 
PROSITE
 PS50330; UIM 
PRINTS