| Tag | Content |
|---|
| CPLM ID | CPLM-021851 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Polycystic kidney disease 2-like 2 protein |
Protein Synonyms/Alias | Polycystin-2L2; Polycystin-L2 |
Gene Name | Pkd2l2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 537 | KAQAKEEKKMQTTDL | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | May function as a subunit of a cation channel and play a role in fertilization. |
Sequence Annotation | MOTIF 126 138 Polycystin motif.
CARBOHYD 115 115 N-linked (GlcNAc...) (Potential).
CARBOHYD 138 138 N-linked (GlcNAc...) (Potential). |
Keyword | Coiled coil; Complete proteome; Glycoprotein; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 621 AA |
Protein Sequence | MSEATWWYRG GTSKHDLHYR REAEVNTTLE ELLLYFIFLI NLCILTFGMV NPHMYYLNKV 60
MSSLFVDTSL PDDERSSFRS IRSITEFWKF MEGPLIDGLY WDSWYGNKQL YSVKNSSRIY 120
YENVLLGIPR VRQLRVRNNT CKVYPAFQSL VSDCYSKYTV ENEDFSDFGL KRNPEWTHTP 180
SSRTAPWHWG FVGVYRDGGY IVTLSKSKSE TKAKFVDLRL NNWISRGTRA VFIDFSLYNA 240
NVNLFCIIRL LAEFPATGGL LTSWQFYSVK LLRYVSYYDY FIASCEVIFC IFLFVFIIQE 300
LRKVNEFKSA YFRSVWNWLE MLLLLLCFLA VSFYAYCNMQ SFLLLGQLLK NTDSYPDFYF 360
LAYWHIYYNN VIAITIFFAW IKIFKFISFN ETMSQLSSTL SRCMKDIVGF AIMFFIIFSA 420
YAQLGFLVFG SQVDDFSTFQ NSIFAQFRIV LGDFNFAGIQ QANWILGPIY FITFIFFVFF 480
VLLNMFLAII NDTYSEVKAD YSIGRRPDFE LGKIIQKSCF NVLEKLRLKK AQAKEEKKMQ 540
TTDLAQRARR DGFDESEIQE AEQMKRWKER LEKKYYSTEI QDDYQPVTQQ EFRELFLYAV 600
ELEKELHYVS LKLNQLMRKL H 621 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; IBA:RefGenome. GO:0005262; F:calcium channel activity; IBA:RefGenome. GO:0005509; F:calcium ion binding; IEA:InterPro. GO:0050982; P:detection of mechanical stimulus; IBA:RefGenome. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |