| Tag | Content |
|---|
| CPLM ID | CPLM-023491 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanine deaminase |
Protein Synonyms/Alias | Guanase; Guanine aminase; Guanine aminohydrolase; GAH |
Gene Name | Gda |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 207 | QKNYSRVKPIVTPRF | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. |
Sequence Annotation | METAL 82 82 Zinc; via tele nitrogen (By similarity).
METAL 84 84 Zinc; via tele nitrogen (By similarity).
METAL 240 240 Zinc; via tele nitrogen (By similarity).
METAL 330 330 Zinc (By similarity).
BINDING 87 87 Substrate (By similarity).
BINDING 213 213 Substrate (By similarity).
BINDING 243 243 Substrate (By similarity).
BINDING 279 279 Substrate (By similarity). |
Keyword | Complete proteome; Direct protein sequencing; Hydrolase; Metal-binding; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 454 AA |
Protein Sequence | MCAARRRELA LIFRGTFVHS TWTCPMEVLR DHLLGVSDSG KIVFLEESSQ QEKLAKEWCF 60
KPCEIRELSH HEFFMPGLVD THIHAPQYAF AGSNVDLPLL DWLNKYTFPT EKRFQSTDVA 120
EEVYTRVVRR TLKNGTTTAC YFGTIHTDSS LILAEITDKF GQRAFVGKVC MDLNNTVPEY 180
KETTEESVKE TERFVSEMLQ KNYSRVKPIV TPRFSLSCTE TLMSELGNIA KTHDLYIQSH 240
ISENREEIEA VKSLYPGYKN YTDVYDKNNL LTNKTVMAHG CYLSEEELNV FSERGASIAH 300
CPNSNLSLSS GLLNVLDVLK HKVKIGLGTD VAGGYSYSML DAIRRAVMVS NVLLINKVNE 360
KSLTLKEVFR LATLGGSQAL GLDREIGNFE VGKDFDALLI NPRASDSPID LFCGDFVGDI 420
SEAVIQKFLY LGDDRNIEEV YVGGKQVVPF SSSV 454 |
Gene Ontology | GO:0008892; F:guanine deaminase activity; IDA:RGD. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006147; P:guanine catabolic process; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |