| Tag | Content |
|---|
| CPLM ID | CPLM-000923 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitogen-activated protein kinase-binding protein 1 |
Protein Synonyms/Alias | JNK-binding protein 1; JNKBP-1 |
Gene Name | MAPKBP1 |
Gene Synonyms/Alias | JNKBP1; KIAA0596 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 600 | IYFRTAQKSGDGVQF | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Involved in JNK signaling pathway (By similarity). |
Sequence Annotation | REPEAT 88 129 WD 1.
REPEAT 132 173 WD 2.
REPEAT 175 213 WD 3.
REPEAT 276 315 WD 4.
REPEAT 342 381 WD 5.
REPEAT 387 436 WD 6.
REPEAT 477 516 WD 7.
REPEAT 519 561 WD 8.
REPEAT 565 606 WD 9.
REPEAT 614 653 WD 10.
REPEAT 659 698 WD 11.
REPEAT 701 740 WD 12. |
Keyword | Alternative splicing; Complete proteome; Polymorphism; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1514 AA |
Protein Sequence | MAVEGSTITS RIKNLLRSPS IKLRRSKAGN RREDLSSKVT LEKVLGITVS GGRGLACDPR 60
SGLVAYPAGC VVVLFNPRKH KQHHILNSSR KTITALAFSP DGKYLVTGES GHMPAVRVWD 120
VAEHSQVAEL QEHKYGVACV AFSPSAKYIV SVGYQHDMIV NVWAWKKNIV VASNKVSSRV 180
TAVSFSEDCS YFVTAGNRHI KFWYLDDSKT SKVNATVPLL GRSGLLGELR NNLFTDVACG 240
RGKKADSTFC ITSSGLLCEF SDRRLLDKWV ELRNIDSFTT TVAHCISVSQ DYIFCGCADG 300
TVRLFNPSNL HFLSTLPRPH ALGTDIASVT EASRLFSGVA NARYPDTIAL TFDPTNQWLS 360
CVYNDHSIYV WDVRDPKKVG KVYSALYHSS CVWSVEVYPE VKDSNQACLP PSSFITCSSD 420
NTIRLWNTES SGVHGSTLHR NILSSDLIKI IYVDGNTQAL LDTELPGGDK ADASLLDPRV 480
GIRSVCVSPN GQHLASGDRM GTLRVHELQS LSEMLKVEAH DSEILCLEYS KPDTGLKLLA 540
SASRDRLIHV LDAGREYSLQ QTLDEHSSSI TAVKFAASDG QVRMISCGAD KSIYFRTAQK 600
SGDGVQFTRT HHVVRKTTLY DMDVEPSWKY TAIGCQDRNI RIFNISSGKQ KKLFKGSQGE 660
DGTLIKVQTD PSGIYIATSC SDKNLSIFDF SSGECVATMF GHSEIVTGMK FSNDCKHLIS 720
VSGDSCIFVW RLSSEMTISM RQRLAELRQR QRGGKQQGPS SPQRASGPNR HQAPSMLSPG 780
PALSSDSDKE GEDEGTEEEL PALPVLAKST KKALASVPSP ALPRSLSHWE MSRAQESVGF 840
LDPAPAANPG PRRRGRWVQP GVELSVRSML DLRQLETLAP SLQDPSQDSL AIIPSGPRKH 900
GQEALETSLT SQNEKPPRPQ ASQPCSYPHI IRLLSQEEGV FAQDLEPAPI EDGIVYPEPS 960
DNPTMDTSEF QVQAPARGTL GRVYPGSRSS EKHSPDSACS VDYSSSCLSS PEHPTEDSES 1020
TEPLSVDGIS SDLEEPAEGD EEEEEEEGGM GPYGLQEGSP QTPDQEQFLK QHFETLASGA 1080
APGAPVQVPE RSESRSISSR FLLQVQTRPL REPSPSSSSL ALMSRPAQVP QASGEQPRGN 1140
GANPPGAPPE VEPSSGNPSP QQAASVLLPR CRLNPDSSWA PKRVATASPF SGLQKAQSVH 1200
SLVPQERHEA SLQAPSPGAL LSREIEAQDG LGSLPPADGR PSRPHSYQNP TTSSMAKISR 1260
SISVGENLGL VAEPQAHAPI RVSPLSKLAL PSRAHLVLDI PKPLPDRPTL AAFSPVTKGR 1320
APGEAEKPGF PVGLGKAHST TERWACLGEG TTPKPRTECQ AHPGPSSPCA QQLPVSSLFQ 1380
GPENLQPPPP EKTPNPMECT KPGAALSQDS EPAVSLEQCE QLVAELRGSV RQAVRLYHSV 1440
AGCKMPSAEQ SRIAQLLRDT FSSVRQELEA VAGAVLSSPG SSPGAVGAEQ TQALLEQYSE 1500
LLLRAVERRM ERKL 1514 |
Gene Ontology | GO:0007256; P:activation of JNKK activity; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |