CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043212
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 
Protein Synonyms/Alias
  
Gene Name
 Gnb1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
15RQEAEQLKNQIRDARubiquitination[1]
23NQIRDARKACADATLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 274 AA 
Protein Sequence
MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT LRGHLAKIYA 60
MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI 120
CSIYNLKTRE GNVRVSRELA GHTGYLSCCR FLDDNQIVTS SGDTTCALWD IETGQQTTTF 180
TGHTGDVMSL SLAPDTRLFV SGACDASAKL WDVREGMCRQ TFTGHESDIN AICFFPNGNA 240
FATGSDDATC RLFDLRADQE LMTYSHDNII CGIT 274 
Gene Ontology
 GO:0044297; C:cell body; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0005834; C:heterotrimeric G-protein complex; IPI:MGI.
 GO:0001917; C:photoreceptor inner segment; IEA:Compara.
 GO:0001750; C:photoreceptor outer segment; IDA:MGI.
 GO:0042622; C:photoreceptor outer segment membrane; IEA:Compara.
 GO:0003924; F:GTPase activity; ISA:MGI.
 GO:0010659; P:cardiac muscle cell apoptotic process; ISO:MGI.
 GO:0008283; P:cell proliferation; IDA:MGI.
 GO:0071456; P:cellular response to hypoxia; ISO:MGI.
 GO:0007204; P:elevation of cytosolic calcium ion concentration; IEA:Compara.
 GO:0007200; P:phospholipase C-activating G-protein coupled receptor signaling pathway; IDA:MGI.
 GO:0007603; P:phototransduction, visible light; ISA:MGI.
 GO:0060041; P:retina development in camera-type eye; IMP:MGI.
 GO:0050909; P:sensory perception of taste; IDA:MGI. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR001632; Gprotein_B.
 IPR016346; Guanine_nucleotide-bd_bsu.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00319; GPROTEINB.
 PR00320; GPROTEINBRPT.