CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000818
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450 2J5 
Protein Synonyms/Alias
 Arachidonic acid epoxygenase; CYPIIJ5 
Gene Name
 Cyp2j5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
73LVLQQFVKKYGNVFSubiquitination[1]
123VRERITGKNGLVVSNubiquitination[1]
135VSNGQTWKEQRRLALubiquitination[1]
246YLPGPHQKIFRNWGKubiquitination[1]
263LFVSHIVKKHEKDWNubiquitination[1]
287AFLIEMQKDPDRTTSubiquitination[1]
388REVTVDTKFNGFHLPubiquitination[1]
412TALHRDPKEWATPEVubiquitination[1]
432FLENGQFKKRESFLPubiquitination[1]
433LENGQFKKRESFLPFubiquitination[1]
444FLPFSMGKRACLGEQubiquitination[1]
477FKPPINEKLSLKFRMubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 METAL 447 447 Iron (heme axial ligand) (By similarity).  
Keyword
 Complete proteome; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 501 AA 
Protein Sequence
MIMFLSSLVT TFWEALHLKT LVLAVVTFLF LINILRSRHP KNYPPGPWRL PFVGNFFQID 60
TKQTHLVLQQ FVKKYGNVFS LELGQSPVVV VSGLPLIKEM FTHLDQNFVN RFMTPVRERI 120
TGKNGLVVSN GQTWKEQRRL ALMALRNFGL GKKSLEERIQ EETHHLVEAI REEGGQPFNP 180
HLKLINAVSN IICSVTFGER FDYEDCQFQE LLQLLDETMH LMGSSAGQLY NGFPCIMKYL 240
PGPHQKIFRN WGKLKLFVSH IVKKHEKDWN PDEPRDFIDA FLIEMQKDPD RTTSFNEENL 300
ISTTLDLFLG GTETTSSTLR WALLYMSSYP EIQENVQAEI DRVIGHKRQV SLSDRESMPY 360
TNAVIHEVQR MGNIVPLNSS REVTVDTKFN GFHLPKGTMI LTNLTALHRD PKEWATPEVF 420
NPEHFLENGQ FKKRESFLPF SMGKRACLGE QLAKSELFIF FSALMQKFTF KPPINEKLSL 480
KFRMGLILSP ASYRICAIPR V 501 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0070330; F:aromatase activity; IEA:EC.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR002401; Cyt_P450_E_grp-I.
 IPR008071; Cyt_P450_E_grp-I_CYP2J-like. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00463; EP450I.
 PR01688; EP450ICYP2J.
 PR00385; P450.