UniProt Accession

 ACRR_ECOLI; P0ACS9; P34000; Q2MBW3 

Genbank Protein ID

 U00734; U82664; U00096; AP009048 

Genbank Nucleotide ID

 AAA67133.1; AAB40218.1; AAC73566.1; BAE76243.1 

Protein Name

 HTH-type transcriptional regulator AcrR 

Protein Synonyms/Alias

 Potential acrAB operon repressor 

Gene Name

 acrR 

Gene Synonyms/Alias

 ybaH; b0464; JW0453 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
39	TSLGEIAKAAGVTRG	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Potential regulator protein for the acrAB genes. 

Sequence Annotation

 DOMAIN 10 70 HTH tetR-type.
 DNA_BIND 33 52 H-T-H motif (Potential).  

Keyword

 3D-structure; Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 215 AA 

Protein Sequence

Gene Ontology

 GO:0008144; F:drug binding; IDA:EcoCyc.
 GO:0043565; F:sequence-specific DNA binding; IDA:EcoCyc.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:EcoCyc.
 GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc.
 GO:0042493; P:response to drug; IDA:EcoCyc.
 GO:0006351; P:transcription, DNA-dependent; IMP:EcoCyc. 

Interpro

 IPR023772; DNA-bd_HTH_TetR-type_CS.
 IPR009057; Homeodomain-like.
 IPR001647; HTH_TetR.
 IPR015893; Tet_transcr_reg_TetR-like_C.
 IPR011075; Tet_transcr_reg_TetR-rel_C.
 IPR013572; Tscrpt_reg_MAATS_C. 

Pfam

 PF08361; TetR_C_2
 PF00440; TetR_N 

SMART

  

PROSITE

 PS01081; HTH_TETR_1
 PS50977; HTH_TETR_2 

PRINTS

 PR00455; HTHTETR.