| Tag | Content |
|---|
| CPLM ID | CPLM-005945 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | tRNA pseudouridine(38/39) synthase |
Protein Synonyms/Alias | Depressed growth-rate protein DEG1; tRNA pseudouridine synthase 3; tRNA pseudouridylate synthase 3; tRNA-uridine isomerase 3 |
Gene Name | DEG1 |
Gene Synonyms/Alias | HRM3; PUS3; YFL001W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 55 | ANKPHSEKFQHIEDN | acetylation | [1] | | 83 | KAKKAPKKFDFSKHN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Formation of pseudouridines at positions 38 and 39 in the anticodon stem and loop of transfer RNAs. |
Sequence Annotation | ACT_SITE 151 151 Nucleophile (By similarity).
BINDING 222 222 Substrate (By similarity). |
Keyword | Complete proteome; Isomerase; Nucleus; Reference proteome; tRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 442 AA |
Protein Sequence | MSNFIRRLVG KMKAISTGTN AIVSKKDSIY ANWSKEQLIR RITELENANK PHSEKFQHIE 60
DNKKRKISQE EVTRSKAKKA PKKFDFSKHN TRFIALRFAY LGWNYNGLAV QKEYTPLPTV 120
EGTILEAMNK CKLVPSMVLQ DYKFSRCGRT DKGVSAMNQV ISLEVRSNLT DEEQRDPTND 180
SREIPYVHVL NQLLPDDIRI SAVCLRPPPN FDARFSCVHR HYKYIFNGKN LNIEKMSKAA 240
SYFVGERDFR NFCKLDGSKQ ITNFKRTIIS SKILPLSETF YCFDLVGSAF LWHQVRCMMA 300
ILFLVGQSLE VPEIVLRLTD IEKTPQRPVY EMANDIPLLL YDCKFPEMDW QEPTVDDYKA 360
IKFTTATEAL TLHYELKAAV CNIFKDVLPT ANTNNFSKTI INLGDGRGKV VGTYVKLEDR 420
SVMEPVEVVN AKYSKKKNNK NK 442 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |