CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042389
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 EF-hand domain-containing protein D2 
Protein Synonyms/Alias
  
Gene Name
 EFHD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
5***XKMFKQYDAGRDacetylation[1]
5***XKMFKQYDAGRDubiquitination[2]
37PQTHLGLKNMIKEVDubiquitination[3]
41LGLKNMIKEVDEDFDubiquitination[2]
91DVSSEGVKGAKSFFEubiquitination[2]
94SEGVKGAKSFFEAKWubiquitination[2]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 179 AA 
Protein Sequence
XKMFKQYDAG RDGFIDLMEL KLMMEKLGAP QTHLGLKNMI KEVDEDFDSK LSFREFLLIF 60
RKAAAGELQE DSGLCVLARL SEIDVSSEGV KGAKSFFEAK WNWVCRWAPR TGSRGSGWQQ 120
LERLPSSALA LQQPQNIGPG HQRVQPLRGG DQGRAGGKEE AGGGDEAAES GLQGAAVHL 179 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 
Pfam
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS50222; EF_HAND_2 
PRINTS