CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025889
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dimethylglycine dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 Dmgdh 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
201ALAAGARKYGALLKYubiquitination[1]
310GPYESQEKMKLQASWubiquitination[1]
427LDPNRYGKWTTTQYTubiquitination[1]
437TTQYTEAKARESYGFubiquitination[1]
469QRVSGLYKTLKSKCSubiquitination[1]
532IDLSPFGKFNIKGRDubiquitination[1]
636YARRVLQKLTSEDLSubiquitination[1]
653AFKFLQTKSFNISDIubiquitination[1]
743EYFVKLNKPADFIGKubiquitination[1]
788ESIWYKGKVVGNTTSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 869 AA 
Protein Sequence
MLRPGALRLR GLALRGSPRR PSSAGLREGQ ESPASPPEWK DRAETVIIGG GCVGVSLAYH 60
LAKAGMRDVV LMEKSELTAG STWHAAGLTT YFHPGINLKK IHYDSIKLYE RLEEETGQVV 120
GFHQPGSIRL ATTPVRVDEF KYQMTRTNWH ATEQYIIEPE KIHELFPLLN MNKILAGLYN 180
PGDGHIDPYS LTMALAAGAR KYGALLKYPA PVTSLKPRPD GTWDVETPQG SVRANRIVNA 240
AGFWAREVGK MIGLDHPLIP VQHQYVVTST IPEVKALKRE LPVLRDLEGS YYLRQERDGL 300
LFGPYESQEK MKLQASWVTH GVPPGFGKEL FESDLDRISD HLEAAMEMIP VLKKADIINV 360
VNGPITYSPD ILPMVGPHQG VRNYWVATGF GYGIIHAGGV GKFLSDWILH GEPPFDLIEL 420
DPNRYGKWTT TQYTEAKARE SYGFNNIVGY PKEERFAGRP TQRVSGLYKT LKSKCSMGFH 480
AGWEQPHWFY KPGQDTQYRP SFRRTNWFEP VGSEYKQVMQ RVGVIDLSPF GKFNIKGRDS 540
TQLLDHLFAN VIPKVGFTNI SHMLTPRGRV YAELTVSQQS PGEFLLITGS GSELHDLRWI 600
EEAAFRGGYD VEIQNITDEF GVLGVAGPYA RRVLQKLTSE DLSDDAFKFL QTKSFNISDI 660
PVTAIRISYT GELGWELYHR REDSATLYER IMSAGQEEGI GDFGTYALNA LRLEKAFRAW 720
GSEMNCDTNP LEAGLEYFVK LNKPADFIGK QALKQIKTEG LKRRLVCLTV ATDDVDPEGN 780
ESIWYKGKVV GNTTSGSYSY SIQKSLAFAY VPVQLSEVGQ QVEAELLGKN YPATIIQEPL 840
VLTEPARARL QKDGKKTNLE KGPSRTTKL 869 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004047; F:aminomethyltransferase activity; IEA:InterPro.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro.
 GO:0006546; P:glycine catabolic process; IEA:InterPro. 
Interpro
 IPR006076; FAD-dep_OxRdtase.
 IPR013977; GCV_T_C.
 IPR006222; GCV_T_N.
 IPR027266; TrmE/GcvT_dom1. 
Pfam
 PF01266; DAO
 PF01571; GCV_T
 PF08669; GCV_T_C 
SMART
  
PROSITE
  
PRINTS