UniProt Accession

 AT1B2_MOUSE; P14231 

Genbank Protein ID

 X16645; X56007; M60897; BC042467; BC058763 

Genbank Nucleotide ID

 CAA34638.1; CAA39482.1; AAH42467.1; AAH58763.1 

Protein Name

 Sodium/potassium-transporting ATPase subunit beta-2 

Protein Synonyms/Alias

 Adhesion molecule in glia; AMOG; Sodium/potassium-dependent ATPase subunit beta-2 

Gene Name

 Atp1b2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
8	MVIQKEKKSCGQVVE	ubiquitination	[1]
18	GQVVEEWKEFVWNPR	ubiquitination	[1]
147	NGVLNYPKRACQFNR	ubiquitination	[1]
276	ATDDERDKFAGRVAF	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. 

Sequence Annotation

 REGION 193 290 immunoglobulin-like (By similarity).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 118 118 N-linked (GlcNAc...).
 CARBOHYD 153 153 N-linked (GlcNAc...) (Potential).
 CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
 CARBOHYD 197 197 N-linked (GlcNAc...) (Potential).
 CARBOHYD 220 220 N-linked (GlcNAc...) (Potential).
 CARBOHYD 238 238 N-linked (GlcNAc...).
 CARBOHYD 250 250 N-linked (GlcNAc...).
 DISULFID 129 150 By similarity.
 DISULFID 160 177 By similarity.
 DISULFID 200 261 By similarity.  

Keyword

 Cell adhesion; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Signal-anchor; Sodium; Sodium transport; Sodium/potassium transport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
 GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. 

Interpro

 IPR000402; Na/K_ATPase_sub_beta. 

Pfam

 PF00287; Na_K-ATPase 

SMART

  

PROSITE

 PS00390; ATPASE_NA_K_BETA_1
 PS00391; ATPASE_NA_K_BETA_2 

PRINTS